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Articles Published Processes
5/18/2015 5:02:00 PM | Browse: 949 | Download: 1190
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Received |
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2014-08-02 12:43 |
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Peer-Review Started |
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2014-08-02 20:18 |
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To Make the First Decision |
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2014-08-27 19:08 |
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Return for Revision |
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2014-09-09 10:14 |
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Revised |
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2014-09-13 17:55 |
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Second Decision |
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2014-11-19 08:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-12-01 13:36 |
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Articles in Press |
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2014-12-01 13:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-04-27 09:39 |
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Publish the Manuscript Online |
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2015-05-18 17:02 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Oral mixture of autologous colon-extracted proteins for the Crohn’s disease: A double-blind trial
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Eran Israeli, Ehud Zigmond, Gadi Lalazar, Athalia Klein, Nilla Hemed, Eran Goldin and Yaron Ilan |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| ENZO Biochem, New York City, NY, United States, and the Roaman-Epstein Liver Research Foundation |
to Ilan Y(in part) |
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| Corresponding Author |
Yaron Ilan, MD, Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, POB 12000, IL-91120 Jerusalem, Israel. ilan@hadassah.org.il |
| Key Words |
Oral tolerance; Crohn’s disease; Natural killer T cells; Immune modulation |
| Core Tip |
Oral administration of the autologous colonic extract could be a safe and effective for the treatment of patients with moderate to severe Crohn’s disease (CD). Increased ratio of CD4+/CD8+ T lymphocytes was noted in subjects with a significant clinical response and may serve as a biomarker for response to therapy. |
| Publish Date |
2015-05-18 17:02 |
| Citation |
Israeli E, Zigmond E, Lalazar G, Klein A, Hemed N, Goldin E, Ilan Y. Oral mixture of autologous colon-extracted proteins for the Crohn’s disease: A double-blind trial. World J Gastroenterol 2015; 21(18): 5685-5694 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i18/5685.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i18.5685 |
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