Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	13059
Country	Greece

Received	2014-08-04 08:29
Peer-Review Started	2014-08-04 11:11
To Make the First Decision	2014-08-28 14:44
Return for Revision	2014-09-03 15:20
Revised	2014-09-14 21:24
Second Decision	2014-11-12 13:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-11-19 11:23
Articles in Press	2014-11-19 11:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-12 21:26
Publish the Manuscript Online	2014-12-18 19:00

ISSN	1948-5190 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding
Manuscript Source	Invited Manuscript
All Author List	Panagiotis Tsibouris, Chissostomos Kalantzis, Periklis Apostolopoulos, Antonios Zalonis, Peter Edward Thomas Isaacs, Mark Hendrickse and Georgios Alexandrakis
Funding Agency and Grant Number	Funding Agency Grant Number Patients or their insurance for capsule endoscopy NIMTS General Hospital
Corresponding Author	Panagiotis Tsibouris, PhD, Consultant Gastroenterologist, Department of Gastroenterology, NIMTS General Hospital, 10-12 Monis Petraki Str, 11521 Athens, Greece. tsibofam@yahoo.com
Key Words	Non-steroidal anti-inflammatory drugs; Aspirin; Wireless capsule endoscopy; Small bowel ulcerative lesions; Peptic ulcer bleeding
Core Tip	Non-steroidal anti-inflammatory drugs (NSAIDs) can frequently cause small bowel ulcerative lesions. In our prospective case control study we found that 95% of elderly patients with peptic ulcer bleeding consuming NSAIDs also presented small bowel erosions and 55% small bowel ulcers. Small bowel ulcerative lesions were 3 times less frequent in patients with a non-bleeding peptic ulcer consuming NSAIDs, and infrequent among patients with a peptic ulcer not receiving NSAIDs. Small bowel ulcers in peptic ulcer bleeders were related with lower entry hemoglobin and increased need for blood transfusion. Moreover, they could be incriminated for unexplained bleeding recurrence despite successful peptic ulcer hemostasis.
Publish Date	2014-12-18 19:00
Citation	Tsibouris P, Kalantzis C, Apostolopoulos P, Zalonis A, Isaacs PET, Hendrickse M, Alexandrakis G. Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding. World J Gastrointest Endosc 2014; 6(12): 612-619
URL	http://www.wjgnet.com/1948-5190/full/v6/i12/612.htm
DOI	http://dx.doi.org/10.4253/wjge.v6.i12.612

Full Article (PDF)	WJGE-6-612.pdf
Manuscript File	13059-Review.doc
Answering Reviewers	13059-Answering reviewers.pdf
Copyright License Agreement	13059-Copyright assignment.pdf
Peer-review Report	13059-Peer review(s).pdf
Scientific Misconduct Check	13059-CrossCheck.jpg
Scientific Editor Work List	13059-Scientific editor work list.pdf