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12/18/2014 7:01:00 PM | Browse: 505 | Download: 335
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 13059
Country of Manuscript Source Greece
Received
2014-08-04 08:29
Peer-Review Started
2014-08-04 11:11
To Make the First Decision
2014-08-28 14:44
Return for Revision
2014-09-03 15:20
Revised
2014-09-14 21:24
Second Decision
2014-11-12 13:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-11-19 11:23
Articles in Press
2014-11-19 11:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-12-12 21:26
Publish the Manuscript Online
2014-12-18 19:00
ISSN 1948-5190 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Prospective Study
Article Title Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding
Manuscript Source Invited Manuscript
All Author List Panagiotis Tsibouris, Chissostomos Kalantzis, Periklis Apostolopoulos, Antonios Zalonis, Peter Edward Thomas Isaacs, Mark Hendrickse and Georgios Alexandrakis
Funding Agency and Grant Number
Funding Agency Grant Number
Patients or their insurance for capsule endoscopy
NIMTS General Hospital
Corresponding author Panagiotis Tsibouris, PhD, Consultant Gastroenterologist, Department of Gastroenterology, NIMTS General Hospital, 10-12 Monis Petraki Str, 11521 Athens, Greece. tsibofam@yahoo.com
Keywords Non-steroidal anti-inflammatory drugs; Aspirin; Wireless capsule endoscopy; Small bowel ulcerative lesions; Peptic ulcer bleeding
Core Tip Non-steroidal anti-inflammatory drugs (NSAIDs) can frequently cause small bowel ulcerative lesions. In our prospective case control study we found that 95% of elderly patients with peptic ulcer bleeding consuming NSAIDs also presented small bowel erosions and 55% small bowel ulcers. Small bowel ulcerative lesions were 3 times less frequent in patients with a non-bleeding peptic ulcer consuming NSAIDs, and infrequent among patients with a peptic ulcer not receiving NSAIDs. Small bowel ulcers in peptic ulcer bleeders were related with lower entry hemoglobin and increased need for blood transfusion. Moreover, they could be incriminated for unexplained bleeding recurrence despite successful peptic ulcer hemostasis.
Publish Date 2014-12-18 19:00
Citation Tsibouris P, Kalantzis C, Apostolopoulos P, Zalonis A, Isaacs PET, Hendrickse M, Alexandrakis G. Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding. World J Gastrointest Endosc 2014; 6(12): 612-619
Url http://www.wjgnet.com/1948-5190/full/v6/i12/612.htm
DOI http://dx.doi.org/10.4253/wjge.v6.i12.612
Full Article (PDF) WJGE-6-612.pdf
Manuscript File 13059-Review.doc
Answering Reviewers 13059-Answering reviewers.pdf
Copyright License Agreement 13059-Copyright assignment.pdf
Peer-review Report 13059-Peer review(s).pdf
Scientific Misconduct Check 13059-CrossCheck.jpg
Scientific Editor Work List 13059-Scientific editor work list.pdf