BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
4/7/2015 6:08:00 PM | Browse: 1168 | Download: 1300
 |
Received |
|
2014-08-04 08:27 |
|
Peer-Review Started |
|
2014-08-04 11:13 |
|
To Make the First Decision |
|
2014-08-27 19:10 |
|
Return for Revision |
|
2014-09-09 08:27 |
|
Revised |
|
2014-09-21 12:19 |
|
Second Decision |
|
2014-11-19 08:42 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2014-12-01 13:37 |
|
Articles in Press |
|
2014-12-01 14:00 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2015-01-12 13:18 |
|
Typeset the Manuscript |
|
2015-03-24 17:29 |
|
Publish the Manuscript Online |
|
2015-04-07 17:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Fucosylation is a common glycosylation type in pancreatic cancer stem cell-like phenotypes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Naoko Terao, Shinji Takamatsu, Tomomi Minehira, Tomoaki Sobajima, Kotarosumitomo Nakayama, Yoshihiro Kamada and Eiji Miyoshi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Japan Society for the Promotion of Science, and partially supported as a research program |
21249038 |
|
| Corresponding Author |
Eiji Miyoshi, MD, Department of Molecular Biochemistry and Clinical Investigation, Osaka University Graduate School of Medicine, 1-7 Yamada-oka, Suita 565-0871, Japan. emiyoshi@sahs.med.osaka-u.ac.jp |
| Key Words |
Anti-cancer drug resistance; Cancer stem cells; Fucosylation; Glycosylation; Pancreatic cancer; Sphere formation |
| Core Tip |
Fucosylation is one of the most important glycosylation events involved in cancer and infla?mmation. In the present study, we investigated oligosaccharide modifications in pancreatic cancer cancer stem cell (CSC)-like cells. Using several models of CSC-like cells, we found that fucosylation is a common type of glycosylation change in pancreatic cancer CSC-like cells. CSCs are known to be preferentially resistant to many current therapies, including various chemotherapeutic agents and radiation treatment. Our present study suggests that the identification of fucosylated glycoproteins derived from pancreatic cancer cells could lead to novel biomarker development for anticancer drug resistance. |
| Publish Date |
2015-04-07 17:13 |
| Citation |
Terao N, Takamatsu S, Minehira T, Sobajima T, Nakayama K, Kamada Y, Miyoshi E. Fucosylation is a common glycosylation type in pancreatic cancer stem cell-like phenotypes. World J Gastroenterol 2015; 21(13): 3876-3887 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i13/3876.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i13.3876 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
