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Articles Published Processes
1/14/2015 10:56:00 AM | Browse: 1267 | Download: 1372
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Received |
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2014-08-04 18:24 |
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Peer-Review Started |
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2014-08-06 15:03 |
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To Make the First Decision |
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2014-09-16 10:58 |
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Return for Revision |
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2014-09-18 15:41 |
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Revised |
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2014-10-09 10:43 |
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Second Decision |
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2014-11-12 14:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-19 10:46 |
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Articles in Press |
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2014-11-19 10:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-05 16:40 |
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Publish the Manuscript Online |
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2015-01-14 10:56 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Recent advances in the HER2 targeted therapy of gastric cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Tasuku Matsuoka and Masakazu Yashiro |
| Funding Agency and Grant Number |
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| Corresponding Author |
Masakazu Yashiro, MD, Oncology Institute of Geriatrics and Medical Science, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. m9312510@med.osaka-cu.ac.jp |
| Key Words |
Human epidermal growth factor receptor 2; Gastric cancer; Targeting therapy; Trastuzumab |
| Core Tip |
This review summarizes the development of diagnostic and therapeutic approach for the patients with human epidermal growth factor receptor 2 (HER2)-overexpressed/amplified gastric cancer. The biology of HER2-dependent signalling is also described. The ToGA trial highlighted the importance of accurate HER2 testing to guide treatment choice of gastric cancer. Future strategies beyond the ToGA trial to address EFGR family, including HER2 pathway are discussed according to current ongoing clinical trials, as well as experimental studies. |
| Publish Date |
2015-01-14 10:56 |
| Citation |
Matsuoka T, Yashiro M. Recent advances in the HER2 targeted therapy of gastric cancer. World J Clin Cases 2015; 3(1): 42-51 |
| URL |
http://www.wjgnet.com/2307-8960/full/v3/i1/42.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v3.i1.42 |
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