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Articles Published Processes
2/11/2015 5:56:00 PM | Browse: 959 | Download: 1158
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Received |
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2014-08-05 11:53 |
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Peer-Review Started |
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2014-08-05 11:53 |
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To Make the First Decision |
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2014-09-15 17:58 |
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Return for Revision |
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2014-09-17 16:50 |
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Revised |
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2014-09-29 19:10 |
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Second Decision |
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2014-11-25 18:02 |
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Accepted by Journal Editor-in-Chief |
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2014-11-26 02:23 |
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Accepted by Executive Editor-in-Chief |
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2014-12-08 16:08 |
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Articles in Press |
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2014-12-08 17:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-01-05 16:42 |
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Typeset the Manuscript |
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2015-01-30 19:36 |
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Publish the Manuscript Online |
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2015-02-11 17:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Tumor regression grades: Potential outcome predictor of locally advanced rectal adenocarcinoma after preoperative radiotherapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Fan Peng, Wei-Dong Yu, Hong-Da Pan, Lin Wang, Ming Li, Yun-Feng Yao, Jun Zhao and Jin Gu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81372593 |
| National Natural Science Foundation of China |
81030040 |
| National Natural Science Foundation of China |
81201965 |
| Beijing Natural Science Foundation |
7132052 |
| National High-tech R&D Program of China (863 Program) |
2012AA02A506 |
| National High-tech R&D Program of China (863 Program) |
SS2014AA020801 |
| Beijing Municipal Administration of Hospitals Special Fund for Clinical Medicine Development |
ZY201410 |
| Beijing Science and Technology Commission |
D0905001000011 |
| Beijing Science and Technology Commission |
D101100050010068 |
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| Corresponding Author |
Jin Gu, MD, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Colorectal Surgery, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing 100142, China. zlgujin@126.com |
| Key Words |
Tumor regression grade; Preoperative radiotherapy; Rectal adenocarcinoma; Disease-free survival |
| Core Tip |
We report that Mandard tumor regression grade (TRG) predicted the outcome of locally advanced rectal adenocarcinoma after preoperative radiotherapy. We examined the correlation of TRG in the prognosis of rectal adenocarcinoma. We found that high Mandard grade was correlated with tumor height, ypT stage, and ypN stage in Mandard poor responders. In univa?riate survival analysis, Mandard bad responders had significantly worse overall survival and disease-free survival (DFS) compared with Mandard good respon?ders. In multivariate survival analysis, Mandard bad responders had significantly worse DFS than Mandard good responders. Mandard good responders had a favorable prognosis. |
| Publish Date |
2015-02-11 17:56 |
| Citation |
Peng YF, Yu WD, Pan HD, Wang L, Li M, Yao YF, Zhao J, Gu J. Tumor regression grades: Potential outcome predictor of locally advanced rectal adenocarcinoma after preoperative radiotherapy. World J Gastroenterol 2015; 21(6): 1851-1856 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i6/1851.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i6.1851 |
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