Publication Name	World Journal of Stem Cells
Manuscript ID	13113
Country	Spain

Received	2014-08-06 08:24
Peer-Review Started	2014-08-06 18:33
To Make the First Decision	2014-09-04 09:26
Return for Revision	2014-09-04 10:47
Revised	2014-09-26 05:04
Second Decision	2014-11-10 15:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-11-10 15:59
Articles in Press	2014-11-10 15:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-02-11 17:18
Publish the Manuscript Online	2015-03-20 10:47

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Review
Article Title	“Second-generation” stem cells for cardiac repair
Manuscript Source	Invited Manuscript
All Author List	Alberto Núñez García, Ricardo Sanz-Ruiz, María Eugenia Fernández Santos and Francisco Fernández-Avilés
Funding Agency and Grant Number
Corresponding Author	Ricardo Sanz-Ruiz, MD, Department of Cardiology, Hospital General Universitario Gregorio Marañón, Doctor Esquerdo 46, 28007 Madrid, Spain. rsanzruiz@hotmail.com
Key Words	Stem cells; Cardiac repair; Myocardial infarction; Heart failure; Second generation
Core Tip	Myocardial infarction and heart failure represent two of the most prevalent and fatal diseases. Stem cell therapies represent a novel approach capable of restoring the cellular loss observed in these conditions. Data from initial human studies have been encouraging but inconclusive. However, refinements in cell populations as well as new stem cell sources are currently being tested in large phase Ⅲ clinical trials after showing positive results in preclinical models and early clinical reports, thus holding a promise for the achievement of a true myocardial regeneration after myocardial infarction. We review here recent developments in this field.
Publish Date	2015-03-20 10:47
Citation	Núñez García A, Sanz-Ruiz R, Fernández Santos ME, Fernández-Avilés F. “Second-generation” stem cells for cardiac repair. World J Stem Cells 2015; 7(2): 352-367
URL	http://www.wjgnet.com/1948-0210/full/v7/i2/352.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i2.352

Full Article (PDF)	WJSC-7-352.pdf
Full Article (Word)	WJSC-7-352.doc
Manuscript File	13113-Review.docx
Answering Reviewers	13113-Answering reviewers.pdf
Copyright License Agreement	13113-Copyright assignment.pdf
Peer-review Report	13113-Peer review(s).pdf
Scientific Misconduct Check	13113-CrossCheck.jpg
Scientific Editor Work List	13113-Scientific editor work list.pdf