Publication Name	World Journal of Diabetes
Manuscript ID	13122
Country	China

Received	2014-08-06 17:58
Peer-Review Started	2014-08-07 08:38
To Make the First Decision	2014-10-28 14:29
Return for Revision	2014-10-31 17:17
Revised	2015-03-04 00:00
Second Decision	2015-03-09 08:58
Accepted by Journal Editor-in-Chief	2015-03-09 11:12
Accepted by Company Editor-in-Chief	2015-03-18 16:35
Articles in Press	2015-03-18 16:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-16 12:02
Publish the Manuscript Online	2015-05-15 19:54

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Research & Experimental Medicine
Manuscript Type	Basic Study
Article Title	Advanced glycation end-product expression is upregulated in the gastrointestinal tract of type 2 diabetic rats
Manuscript Source	Invited Manuscript
All Author List	Peng-Min Chen, Hans Gregersen and Jing-Bo Zhao
Funding Agency and Grant Number	Funding Agency Grant Number Karen Elise Jensens Foundation
Corresponding Author	Hans Gregersen, Professor, GIOME Center, College of Bioengineering, Chongqing University, 83 Shabei Road, Chongqing 400045, China. hag@giome.org
Key Words	Diabetes mellitus; Gastrointestinal compli­cations; Advanced glycation end products; Receptor of advanced glycation end products
Core Tip	Changes in advanced glycation end products (AGEs) and their receptor (RAGE) expression in the gastrointestinal (GI) tract in type 2 diabetic rats were studied. The AGE and RAGE were widely distributed in epithelial cells of all segments as well as in striated muscle cells in the esophagus. RAGE also distributed in neurons in all segments. Up-regulated AGE and RAGE expression was found in the GI tract of GK diabetic rats. The altered AGE and RAGE may be a contributing factor for GI dysfunction in type 2 diabetic patients.
Publish Date	2015-05-15 19:54
Citation	Chen PM, Gregersen H, Zhao JB. Advanced glycation end-product expression is upregulated in the gastrointestinal tract of type 2 diabetic rats. World J Diabetes 2015; 6(4): 662-672
URL	http://www.wjgnet.com/1948-9358/full/v6/i4/662.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i4.662

Full Article (PDF)	WJD-6-662.pdf
Full Article (Word)	WJD-6-662.doc
Manuscript File	13122-Review.docx
Answering Reviewers	13122-Answering reviewers.pdf
Biostatistics Review Certificate	13122-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	13122-Conflict of interest statement.pdf
Copyright License Agreement	13122-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	13122-Institutional animal care and use committee statement.pdf
Peer-review Report	13122-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	13122-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	13122-Scientific misconduct check.pdf
Scientific Editor Work List	13122-Scientific editor work list.pdf