Publication Name	World Journal of Gastroenterology
Manuscript ID	13135
Country	Japan

Received	2014-08-07 08:15
Peer-Review Started	2014-08-08 09:43
To Make the First Decision	2014-09-27 16:57
Return for Revision	2014-09-30 14:39
Revised	2014-09-02 00:00
Second Decision	2014-11-27 21:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-12-01 13:47
Articles in Press	2014-12-01 14:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-02-12 08:56
Publish the Manuscript Online	2015-03-09 15:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Protracted anaphylaxis developed after peginterferon -2a administration for chronic hepatitis C
Manuscript Source	Unsolicited Manuscript
All Author List	Akihiko Sakatani, Yoshinori Doi, Takaaki Matsuda, Yasutaka Sasai, Naohiro Nishida, Megumi Sakamoto, Naoto Uenoyama, Yoshiya Matsumoto and Kazuo Kinoshita
Funding Agency and Grant Number
Corresponding Author	Akihiko Sakatani, MD, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. akihiko-sakatani@umin.net
Key Words	Peginterferon -2a; Anaphylaxis; Anaphylactic shock; Protracted anaphylaxis; Chronic hepatitis C
Core Tip	This is the first report that describes a case involving anaphylactic shock that developed after peginterferon administration. Moreover, our case showed protracted anaphylaxis, in which symptoms appear hours after exposure to the causative substances and temporarily improve with treatment but recur twice within hours. Protracted anaphylaxis is rare; its incidence accounts for less than 20% of all cases of anaphylaxis. There are few case reports regarding this condition, and its pathophysiology has not yet been established.
Publish Date	2015-03-09 15:58
Citation	Sakatani A, Doi Y, Matsuda T, Sasai Y, Nishida N, Sakamoto M, Uenoyama N, Matsumoto Y, Kinoshita K. Protracted anaphylaxis developed after peginterferon -2a administration for chronic hepatitis C. World J Gastroenterol 2015; 21(9): 2826-2829
URL	http://www.wjgnet.com/1007-9327/full/v21/i9/2826.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i9.2826

Full Article (PDF)	WJG-21-2826.pdf
Full Article (Word)	WJG-21-2826.doc
Manuscript File	13135-Review.doc
Answering Reviewers	13135-Answering reviewers.pdf
Copyright License Agreement	13135-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	13135-Language certificate.pdf
Peer-review Report	13135-Peer review(s).pdf
Scientific Misconduct Check	13135-CrossCheck.jpg
Scientific Editor Work List	13135-Scientific editor work list.pdf