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Articles Published Processes
5/18/2015 5:02:00 PM | Browse: 1082 | Download: 1167
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Received |
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2014-08-08 08:49 |
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Peer-Review Started |
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2014-08-08 11:19 |
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To Make the First Decision |
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2014-08-27 19:11 |
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Return for Revision |
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2014-08-28 10:37 |
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Revised |
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2014-09-16 15:34 |
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Second Decision |
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2014-11-10 16:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-19 09:29 |
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Articles in Press |
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2014-11-19 09:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-04-27 09:52 |
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Publish the Manuscript Online |
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2015-05-18 17:02 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Similar efficacy and safety of tenofovir in Asians and non-Asians with chronic hepatitis B
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Calvin Q Pan, Sing Chan, Huy Trinh, Alan Yao, Ho Bae and Lillian Lou |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Gilead Sciences |
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| Editorial support was provided by Carol Lovegrove, associated with Elements Communications |
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| Gilead Sciences |
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| Corresponding Author |
Calvin Q Pan, MD, Professor, Division of Gastroenterology, Department of Medicine, New York University Langone Medical Center, New York University School of Medicine, 132-21 Forty First Ave, Flushing, New York City, NY 11355, United States. cpan11355@yahoo.com |
| Key Words |
Chronic hepatitis B; Tenofovir; Asian patients; Fibrosis; High viral load |
| Core Tip |
Although a substantial proportion of the worldwide hepatitis B virus-infected population is Asian, this is often not reflected in clinical trial populations. Comparison of data from Asian and non-Asian patients is important to provide a better understanding of treatment outcome in Asian populations. Our analysis is the first and largest to compare early (48 wk) response to tenofovir disoproxil fumarate (TDF) in Asian and non-Asian patients during large-scale clinical studies. Overall, TDF demonstrated similar viral suppression, normalization of alanine aminotransaminase and improvements in liver fibrosis, with no resistance, in all cohorts, irrespective of baseline hepatitis B e antigen status and viral load. |
| Publish Date |
2015-05-18 17:02 |
| Citation |
Pan CQ, Chan S, Trinh H, Yao A, Bae H, Lou L. Similar efficacy and safety of tenofovir in Asians and non-Asians with chronic hepatitis B. World J Gastroenterol 2015; 21(18): 5524-5531 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i18/5524.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i18.5524 |
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