Publication Name	World Journal of Clinical Oncology
Manuscript ID	13222
Country	Australia

Received	2014-08-13 09:23
Peer-Review Started	2014-08-13 19:08
To Make the First Decision	2014-09-28 13:58
Return for Revision	2014-09-29 19:16
Revised	2014-10-10 16:39
Second Decision	2014-10-29 18:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-10-29 18:59
Articles in Press	2014-10-29 18:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-20 11:24
Publish the Manuscript Online	2014-12-11 14:23

ISSN	2218-4333 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Saleh A Almatroodi, Christine F McDonald, Allison L Collins, Ian A Darby and Dodie S Pouniotis
Funding Agency and Grant Number	Funding Agency Grant Number Institute for Breathing and Sleep, Austin Health, Heidelberg, VIC 3084, Australia School of Medical Sciences, RMIT University, PO Box 71, Bundoora, VIC 3083, Australia
Corresponding Author	Saleh A Almatroodi, PhD candidate, School of Medical Sciences, RMIT University, PO Box 71, Bundoora, VIC 3083, Australia. saleh.almatroodi@rmit.edu.au
Key Words	Lung cancer; Monocyte; Phenotype; Polarisation; Tumour progression; Tumour regression
Core Tip	Monocytes perform a critical role in immune system and have similar phenotype as seen in M1 (classically activated) and M2 (alternatively activated) tumour-associated macrophage. Nevertheless, monocyte phenotypes in human lung cancer patients are not fully understood and further investigation are really needed. Our study examines the M1 and M2 monocyte phenotypes in patients with non-small lung carcinoma [non-small cell lung cancer (NSCLC)] compared to non-cancer controls. This study indicated that freshly isolated peripheral blood monocytes from patients with NSCLC do not show an altered phenotype and/or cytokines secretion. These outcomes might enhance the knowledge regarding the connections between monocyte-macrophage phenotype and tumour progression.
Publish Date	2014-12-11 14:23
Citation	Almatroodi SA, McDonald CF, Collins AL, Darby IA, Pouniotis DS. Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer. World J Clin Oncol 2014; 5(5): 1078-1087
URL	http://www.wjgnet.com/2218-4333/full/v5/i5/1078.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i5.1078

Full Article (PDF)	WJCO-5-1078.pdf
Full Article (Word)	WJCO-5-1078.doc
Manuscript File	13222-Review.doc
Answering Reviewers	13222-Answering reviewers.pdf
Copyright License Agreement	13222-Copyright assignment.pdf
Peer-review Report	13222-Peer review(s).pdf
Scientific Misconduct Check	13222-CrossCheck.jpg
Scientific Editor Work List	13222-Scientific editor work list.pdf