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Publication Name World Journal of Gastroenterology
Manuscript ID 1326
Country Canada
Received
2012-12-03 05:18
Peer-Review Started
2012-12-04 15:04
To Make the First Decision
2013-01-17 11:01
Return for Revision
2013-01-21 14:34
Revised
Second Decision
2013-04-15 16:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-04-16 07:50
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-06-25 04:22
Typeset the Manuscript
2013-07-17 09:10
Publish the Manuscript Online
2013-07-29 11:18
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Neurotensin receptor 1 overexpression in inflammatory bowel diseases and colitis-associated neoplasia
Manuscript Source Invited Manuscript
All Author List Xianyong Gui, Shuhong Liu, Yuchu Yan and Zuhua Gao
Funding Agency and Grant Number
Funding Agency Grant Number
Calgary Laboratory Services Internally Supported Research RS09-533
Corresponding Author Xianyong Gui, MD, PhD, Calgary Laboratory Services and Department of Pathology and Laboratory Medicine, University of Calgary, 1403-29 Street NW, Calgary, Alberta T2N 2T9, Canada. xsean.gui@cls.ab.ca
Key Words Neurotensin; Neurotensin receptor; Inflammatory bowel diseases; Dysplasia; Colitis-associated neoplasia; Dysplasia-associated lesion or mass; Sporadic adenoma; Colorectal carcinoma
Core Tip Neurotensin receptor 1 (NTSR1) in colonic epithelial cells is overexpressed in inflammatory bowel diseases, in a stepwise fashion with the sequential progress from inflammation to low-grade dysplasia, high-grade dysplasia, and carcinoma. Both colitis-associated and sporadic dysplasia/carcinoma showed a similar pattern of NTSR1 overexpression. NTSR1 could be a potential pharmacological target in the treatment of inflammatory bowel diseases and prevention of colitis-associated neoplasia.
Publish Date 2013-07-29 11:18
Citation Gui X, Liu S, Yan Y, Gao Z. Neurotensin receptor 1 overexpression in inflammatory bowel diseases and colitis-associated neoplasia. World J Gastroenterol 2013; 19(28): 4504-4510
URL http://www.wjgnet.com/1007-9327/full/v19/i28/4504.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i28.4504
Full Article (PDF) WJG-19-4504.pdf
Manuscript File 1326-Review.doc
Answering Reviewers 1326-Answering reviewers.pdf
Copyright License Agreement 1326-Copyright assignment.pdf
Peer-review Report 1326-Peer review.pdf
Scientific Editor Work List 1326-Scientific editor work list.doc