Publication Name	World Journal of Gastroenterology
Manuscript ID	13298
Country	Brazil

Received	2014-08-16 10:33
Peer-Review Started	2014-08-16 19:18
To Make the First Decision	2014-09-15 16:14
Return for Revision	2014-09-17 22:34
Revised	2014-10-01 03:11
Second Decision	2014-10-21 17:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-10-21 18:02
Articles in Press	2014-10-21 18:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-11-24 22:16
Typeset the Manuscript	2015-01-23 17:39
Publish the Manuscript Online	2015-02-09 17:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test
Manuscript Source	Unsolicited Manuscript
All Author List	Márcia Soares-Mota, Tianny A Silva, Luanda M Gomes, Marco AS Pinto, Laura MC Mendonça, Maria Lúcia F Farias, Tiago Nunes, Andrea Ramalho and Cyrla Zaltman
Funding Agency and Grant Number
Corresponding Author	Dr. Márcia Soares-Mota, Instituto de Nutrição Josué de Castro, Federal University of Rio de Janeiro, Rua Prof Rodolpho Paulo Rocco 255, Ilha do Fundão, Rio de Janeiro 21941-913, Brazil. msoares@nutricao.ufrj.br
Key Words	Crohn’s disease; Vitamin A; Serum retinol; Relative dose response test; Body composition
Core Tip	In this study, a higher prevalence of vitamin A deficiency was detected in Crohn’s disease (CD) patients compared with healthy controls by measuring serum retinol levels and the relative dose-response test. According to the relative dose-response test, almost 40% of the CD patients had inadequate hepatic vitamin A stores, which was three times the value found in healthy controls. CD Patients with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency. There was no association between vitamin A deficiency and its dietary intake, ileal location, presence of disease activity and prior bowel resections.
Publish Date	2015-02-09 17:58
Citation	Soares-Mota M, Silva TA, Gomes LM, Pinto MAS, Mendonça LMC, Farias MLF, Nunes T, Ramalho A, Zaltman C. High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test. World J Gastroenterol 2015; 21(5): 1614-1620
URL	http://www.wjgnet.com/1007-9327/full/v21/i5/1614.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i5.1614

Full Article (PDF)	WJG-21-1614.pdf
Full Article (Word)	WJG-21-1614.doc
Manuscript File	13298-Review.doc
Answering Reviewers	13298-Answering reviewers.pdf
Copyright License Agreement	13298-Copyright assignment.pdf
Peer-review Report	13298-Peer review.pdf
Scientific Misconduct Check	13298-CorssCheck.jpg
Scientific Editor Work List	13298-Scientific editor work list.pdf