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Articles Published Processes
4/7/2015 6:08:00 PM | Browse: 1247 | Download: 1508
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Received |
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2014-08-16 20:35 |
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Peer-Review Started |
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2014-08-17 19:17 |
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To Make the First Decision |
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2014-09-15 16:14 |
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Return for Revision |
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2014-09-17 22:36 |
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Revised |
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2014-10-07 09:16 |
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Second Decision |
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2014-11-11 10:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-11 10:38 |
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Articles in Press |
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2014-11-11 11:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-03-21 19:22 |
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Publish the Manuscript Online |
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2015-04-07 17:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Differentiation of acute and chronic hepatitis B in IgM anti-HBc positive patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ji Won Park, Kyeong Min Kwak, Sung Eun Kim, Myoung Kuk Jang, Dong Joon Kim, Myung Seok Lee, Hyoung Su Kim and Choong Kee Park |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hallym University Medical Center |
HURF-2013-31 |
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| Corresponding Author |
Hyoung Su Kim, MD, Department of Internal Medicine, Hallym University Sacred Heart Hospital of Hallym University Medical Center, 445, Gildong, Kangdong-gu, Seoul 134-701, South Korea. hskim@hallym.or.kr |
| Key Words |
Acute hepatitis; Differential diagnosis; Chronic hepatitis; Hepatitis B virus |
| Core Tip |
Distinguishing between acute hepatitis B (AHB) and chronic hepatitis B with acute exacerbation (CHB-AE) is important because of the different prognosis and treatment strategy. However, distinguishing AHB and CHB-AE is difficult due to their similar clinical features and serologic profiles, especially in patients with IgM anti-HBc positivity. This is the first study to differentiate between AHB and CHB-AE in a distinct group of subjects with positive IgM anti-HBc. The quantitative determination of IgM anti-HBc was useful for differentiating AHB from CHB-AE in patients IgM anti-HBc positive. The combination of serum IgM anti-HBc ≥ 8 S/CO ratio with HBV-DNA levels < 5.5 log10 IU/mL could effectively distinguish AHB from CHB-AE. |
| Publish Date |
2015-04-07 17:13 |
| Citation |
Park JW, Kwak KM, Kim SE, Jang MK, Kim DJ, Lee MS, Kim HS, Park CK. Differentiation of acute and chronic hepatitis B in IgM anti-HBc positive patients. World J Gastroenterol 2015; 21(13): 3953-3959 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i13/3953.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i13.3953 |
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