Publication Name	World Journal of Gastroenterology
Manuscript ID	13321
Country	China

Received	2014-08-17 14:16
Peer-Review Started	2014-08-17 14:18
First Decision by Editorial Office Director
Return for Revision	2014-09-17 12:18
Revised	2014-09-30 12:14
Publication Fee Transferred
Second Decision by Editor	2014-11-25 18:02
Second Decision by Editor-in-Chief	2014-11-25 23:47
Final Decision by Editorial Office Director	2014-12-08 16:09
Articles in Press	2014-12-08 17:17
Edit the Manuscript by Language Editor	2014-12-31 01:21
Typeset the Manuscript	2015-02-09 15:03
Publish the Manuscript Online	2015-02-28 17:07

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Basic Study
Article Title	Biological effects of low-dose-rate irradiation of pancreatic carcinoma cells in vitro using 125I seeds
Manuscript Source	Unsolicited Manuscript
All Author List	Zhong-Min Wang, Jian Lu, Li-Yun Zhang, Xiao-Zhu Lin, Ke-Min Chen, Zhi-Jin Chen, Fen-Ju Liu, Fu-Hua Yan, Gao-Jun Teng and Ai-Wu Mao
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of China 81271682 (partly) Science and Technology Commission of Shanghai Municipality 11JC1407400 (partly) Luwan District Science and Technology Commission of Shanghai LKW1104 (partly) Medical Key Specialty of Shanghai Municipality ZK2012A20 (partly)
Corresponding Author	Ai-Wu Mao, MD, Professor, Department of Interventional Radiology, Shanghai St. Luke’s Hospital, No. 786 Yu Yuan Road, Shanghai 200050, China. james0722@163.com
Key Words	125I radioactive seeds; Biological effects; Pancreatic cancer; SW1990; PANC-1
Core Tip	We compared the radiobiological effects observed in SW1990 and PANC-1 pancreatic cancer cell lines after irradiation with 125I seeds through a clonogenic cell survival assay and 3H-TdR incorporation experiment. Continuous low-dose-rate irradiation with 125I seeds was found to induce apoptosis and G2/M cell cycle arrest.
Publish Date	2015-02-28 17:07
Citation	Wang ZM, Lu J, Zhang LY, Lin XZ, Chen KM, Chen ZJ, Liu FJ, Yan FH, Teng GJ, Mao AW. Biological effects of low-dose-rate irradiation of pancreatic carcinoma cells in vitro using 125I seeds. World J Gastroenterol 2015; 21(8): 2336-2342
URL	http://www.wjgnet.com/1007-9327/full/v21/i8/2336.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i8.2336

Full Article (PDF)	WJG-21-2336.pdf
Full Article (Word)	WJG-21-2336.doc
Manuscript File	13321-Review.doc
Answering Reviewers	13321-Answering reviewers.pdf
Copyright License Agreement	13321-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	13321-Language certificate.pdf
Peer-review Report	13321-Peer review(s).pdf
Scientific Editor Work List	13321-Scientific editor work list.pdf