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Articles Published Processes
3/1/2015 11:51:00 AM | Browse: 987 | Download: 1287
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Received |
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2014-08-19 16:57 |
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Peer-Review Started |
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2014-08-20 15:40 |
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To Make the First Decision |
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2014-09-27 15:07 |
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Return for Revision |
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2014-10-11 11:57 |
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Revised |
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2014-11-06 22:09 |
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Second Decision |
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2014-12-16 15:30 |
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Accepted by Journal Editor-in-Chief |
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2014-12-17 03:30 |
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Accepted by Company Editor-in-Chief |
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2014-12-22 17:09 |
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Articles in Press |
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2014-12-22 17:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-01-21 04:28 |
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Typeset the Manuscript |
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2015-02-08 18:00 |
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Publish the Manuscript Online |
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2015-02-28 17:07 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Coexpression of MYC and BCL-2 predicts prognosis in primary gastrointestinal diffuse large B-cell lymphoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bing Xia, Le Zhang, Shan-Qi Guo, Xiao-Wu Li, Fu-Lian Qu, Hai-Feng Zhao, Lian-Yu Zhang, Bao-Cun Sun, James You and Yi-Zhuo Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
30672208 |
| National Natural Science Foundation of China |
81270603 |
| National Natural Science Foundation of China |
31301161 |
| Tianjin Natural Science Foundation of China |
13JCYBJC22800 |
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| Corresponding Author |
Yi-Zhuo Zhang, Professor, Department of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China. yizhuozhang111@163.com |
| Key Words |
MYC; BCL-2; Survival; Primary gastrointestinal diffuse large B-cell lymphoma; Prognosis |
| Core Tip |
We investigated MYC and BCL-2 coexpression in primary gastrointestinal diffuse large B-cell lymphoma (PGI-DLBCL) and explored its associations with patients’ clinical parameters. In contrast to previously published results about MYC/BCL-2 coexpression in DLBCL, this study focused on PGI-DLBCL. Although PGI-DLBCL is rare, we had a large collection of 60 PGI-DLBCL cases to test the protein and mRNA levels of MYC and BCL-2. We found that MYC+/BCL-2+ patients have worse chemotherapy response and poorer prognosis than patients who only express one of the two proteins, suggesting that assessment of MYC and BCL-2 expression has clinical significance in predicting clinical outcomes of PGI-DLBCL patients. |
| Publish Date |
2015-02-28 17:07 |
| Citation |
Xia B, Zhang L, Guo SQ, Li XW, Qu FL, Zhao HF, Zhang LY, Sun BC, You J, Zhang YZ. Coexpression of MYC and BCL-2 predicts prognosis in primary gastrointestinal diffuse large B-cell lymphoma. World J Gastroenterol 2015; 21(8): 2433-2442 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i8/2433.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i8.2433 |
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