Publication Name	World Journal of Transplantation
Manuscript ID	13369
Country	Canada

Received	2014-08-20 08:19
Peer-Review Started	2014-08-20 13:43
To Make the First Decision	2014-09-28 13:45
Return for Revision	2014-10-08 05:58
Revised	2014-10-13 05:05
Second Decision	2015-01-22 20:43
Accepted by Journal Editor-in-Chief	2015-01-24 04:36
Accepted by Executive Editor-in-Chief	2015-02-02 20:07
Articles in Press	2015-02-02 20:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-17 14:19
Publish the Manuscript Online	2015-03-24 17:37

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Review
Article Title	Bioengineered stem cells as an alternative for islet cell transplantation
Manuscript Source	Invited Manuscript
All Author List	Sarah J Moore, Boris L Gala-Lopez, Andrew R Pepper, Rena L Pawlick and AM James Shapiro
Funding Agency and Grant Number	Funding Agency Grant Number Collaborative Research and Innovation Opportunities (CRIO)-Alberta Innovates health Solutions Diabetes Research Institute Foundation of Canada Canadian National Transplant Research Program Alberta Diabetes Institute Clinical Islet Transplant Program NIH Funding through the Collaborative Islet Transplant Consortium to Shapiro AMJ Canada Research Chair in Transplantation Surgery and Regenerative Medicine to Shapiro AMJ
Corresponding Author	AM James Shapiro, MD, PhD, FRCS (Eng), FRCSC, MSM, Fellow of the Royal Society of Canada, Canada Research Chair in Transplant Surgery and Regenerative Medicine, Professor of Surgery, Medicine and Surgical Oncology, Clinical Islet Transplant Program, University of Alberta, 2000 College Plaza, 8215 112th St, Edmonton AB T6G 2C8, Canada. amjs@islet.ca
Key Words	Islet transplantation; Hypoxia; Stem cell; Diabetes
Core Tip	This paper gives a historical overview of the use of islet transplantation for the treatment of type 1 diabetes mellitus. Islet cell transplantation has seen enormous development over the years; however, this has not been without its limitations. The aim of this paper is to provide an overview of the feasibility of an alternative cell source for clinical islet transplantation.
Publish Date	2015-03-24 17:37
Citation	Moore SJ, Gala-Lopez BL, Pepper AR, Pawlick RL, Shapiro AMJ. Bioengineered stem cells as an alternative for islet cell transplantation. World J Transplant 2015; 5(1): 1-10
URL	http://www.wjgnet.com/2220-3230/full/v5/i1/1.htm
DOI	http://dx.doi.org/10.5500/wjt.v5.i1.1

Manuscript File	13369-Review.docx
Answering Reviewers	13369-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13369-Conflict-of-interest statement.pdf
Copyright License Agreement	13369-Copyright assignment.pdf
Peer-review Report	13369-Peer-review(s).pdf
Scientific Misconduct Check	13369-CrossCheck.jpg
Scientific Editor Work List	13369-Scientific editor work list.pdf