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4/15/2015 11:01:00 AM | Browse: 748 | Download: 866
Publication Name World Journal of Gastroenterology
Manuscript ID 13374
Country China
Received
2014-08-20 09:08
Peer-Review Started
2014-08-20 18:06
To Make the First Decision
2014-10-29 15:07
Return for Revision
2014-11-04 16:39
Revised
2014-11-17 14:53
Second Decision
2014-11-27 13:05
Accepted by Journal Editor-in-Chief
2014-11-27 18:14
Accepted by Company Editor-in-Chief
2014-12-08 16:11
Articles in Press
2014-12-08 17:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-01-20 12:04
Typeset the Manuscript
2015-03-27 17:02
Publish the Manuscript Online
2015-04-15 11:01
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Preparation of magnetic resonance probes using one-pot method for detection of hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List You-Wei Li, Zheng-Guang Chen, Zhou-She Zhao, Hong-Li Li, Ji-Chen Wang and Zong-Ming Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81071996
Corresponding Author Zong-Ming Zhang, MD, PhD, Professor, Director, Department of General Surgery, Beijing Electric Power Hospital, Capital Medical University, No. 1 Taipingqiaoxili, Fengtai District, Beijing 100073, China. zhangzongming@mail.tsinghua.edu.cn
Key Words Hepatocellular carcinoma; Ultrasmall superparamagnetic iron oxide nanoparticles; Specific probe; One-pot method; Magnetic resonance imaging
Core Tip The preparation process of magnetic resonance probes should be as simple as possible in order to have mass production. We developed a method named one-pot method by modifying the traditional methods to prepare an anti-glypican 3-ultrasmall superparamagnetic iron oxide nanoparticle (USPION) probe and an anti-α-fetoprotein-USPION probe and determined their physical and chemical properties and bioactivity. The results showed that this method is simple and convenient to synthesize the magnetic resonance molecular probes. The synthesized probes entered into the specific cells in vitro.
Publish Date 2015-04-15 11:01
Citation Li YW, Chen ZG, Zhao ZS, Li HL, Wang JC, Zhang ZM. Preparation of magnetic resonance probes using one-pot method for detection of hepatocellular carcinoma. World J Gastroenterol 2015; 21(14): 4275-4283
URL http://www.wjgnet.com/1007-9327/full/v21/i14/4275.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i14.4275
Full Article (PDF) WJG-21-4275.pdf
Full Article (Word) WJG-21-4275.doc
Manuscript File 13374-Review.doc
Answering Reviewers 13374-Answering reviewers.pdf
Copyright License Agreement 13374-Copyright assignment.pdf
Peer-review Report 13374-Peer review(s).pdf
Scientific Misconduct Check 13374-CrossCheck.jpg
Scientific Editor Work List 13374-Scientific editor work list.pdf