BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/8/2015 2:17:00 PM | Browse: 1135 | Download: 1373
 |
Received |
|
2014-08-21 08:54 |
|
Peer-Review Started |
|
2014-08-21 11:53 |
|
To Make the First Decision |
|
2014-09-28 13:45 |
|
Return for Revision |
|
2014-10-08 14:00 |
|
Revised |
|
2014-12-19 00:00 |
|
Second Decision |
|
2014-12-25 18:06 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2014-12-31 13:16 |
|
Articles in Press |
|
2014-12-31 13:16 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2015-04-09 09:03 |
|
Publish the Manuscript Online |
|
2015-05-08 14:17 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Review |
| Article Title |
Pathogenesis of glomerular haematuria
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Claudia Yuste, Eduardo Gutierrez, Angel Manuel Sevillano, Alfonso Rubio-Navarro, Juan Manuel Amaro-Villalobos, Alberto Ortiz, Jesus Egido, Manuel Praga and Juan Antonio Moreno |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| FIS |
CP10/00479 |
| FIS |
PI13/00802 |
| FIS |
PI14/00883 |
| Spanish Society of Nephrology |
to Moreno JA |
| Institute of Research Queen Sophia, FRIAT and ISCIII fund |
PI10/00072(to Egido J) |
|
| Corresponding Author |
Juan Antonio Moreno, PhD, Renal, Vascular and Diabetes Research Lab, IIS-Fundación Jiménez Díaz, Autonoma University (UAM), Av. Reyes Católicos 2, 28040 Madrid, Spain. jamor_eno@fjd.es |
| Key Words |
Haematuria; Pathogenesis; Glomerular filtration barrier; Dysmorphic red blood cells; Chronic kidney disease; Microscopic haematuria |
| Core Tip |
Recent advances suggest that glomerular haematuria may be a negative prognostic factor for renal function outcome. A more fragile and easily ruptured glomerular filtration barrier (GFB) may be responsible for glomerular bleeding. Several factors have been associated to this pathogenic process, including: (1) genetic alteration of GFB components, leading to a more fragile and easily ruptured GFB structure; (2) aberrant deposition of toxic molecules in the GFB; and (3) enhanced inflammatory response, as reported in autoimmune diseases, infections, or primary glomerulonephritis. In this review we fully describe these pathological mechanisms, with special interest in haematuric diseases and their renal morphological findings. |
| Publish Date |
2015-05-08 14:17 |
| Citation |
Yuste C, Gutierrez E, Sevillano AM, Rubio-Navarro A, Amaro-Villalobos JM, Ortiz A, Egido J, Praga M, Moreno JA. Pathogenesis of glomerular haematuria. World J Nephrol 2015; 4(2): 185-195 |
| URL |
http://www.wjgnet.com/2220-6124/full/v4/i2/185.htm |
| DOI |
http://dx.doi.org/10.5527/wjn.v4.i2.185 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
