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Articles Published Processes
12/13/2014 7:02:00 PM | Browse: 886 | Download: 1019
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Received |
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2014-08-22 08:54 |
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Peer-Review Started |
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2014-08-22 10:49 |
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To Make the First Decision |
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2014-10-14 17:35 |
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Return for Revision |
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2014-10-20 08:15 |
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Revised |
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2014-10-28 23:21 |
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Second Decision |
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2014-11-10 15:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-10 16:13 |
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Articles in Press |
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2014-11-10 16:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-11-28 15:50 |
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Publish the Manuscript Online |
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2014-12-13 19:01 |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Topic Highlights |
Article Title |
Recent advances on the association of apoptosis in chronic non healing diabetic wound
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Manuscript Source |
Invited Manuscript |
All Author List |
Awadhesh K Arya, Richik Tripathi, Santosh Kumar and Kamlakar Tripathi |
Funding Agency and Grant Number |
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Corresponding Author |
Kamlakar Tripathi, Professor, Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, Varanasi 221005,
India. kamlakar_tripathi@yahoo.co.in
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Key Words |
Apoptosis; Diabetes mellitus; Diabetic foot; Chronic wound; Oxidative stress |
Core Tip |
Uncontrolled diabetes mellitus lead to the chronic non healing wound which further can escort to the Ischemia and coronary artery disease. Reports suggested that the involvement of various mechanisms in the development of chronic non healing wound in patients with diabetes mellitus, among which the oxidative stress plays a pivotal role which then leading to the enhanced apoptosis of lymphocytes, may be playing a critical role in the delay of wound healing. Connexins are gap junction protein and their upregulation during diabetes might be leads to improper gap junction formation attributing to the passage of various, apoptotic and inflammatory signals thereby resulting in delayed healing of chronic diabetic ulcers.
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Publish Date |
2014-12-13 19:01 |
Citation |
Arya AK, Tripathi R, Kumar S, Tripathi K. Recent advances on the association of apoptosis in chronic non healing diabetic wound. World J Diabetes 2014; 5(6): 756-762 |
URL |
http://www.wjgnet.com/1948-9358/full/v5/i6/756.htm |
DOI |
http://dx.doi.org/10.4239/wjd.v5.i6.756 |
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