Publication Name	World Journal of Stem Cells
Manuscript ID	13418
Country	Germany

Received	2014-08-22 08:31
Peer-Review Started	2014-08-22 15:05
To Make the First Decision	2014-09-28 13:45
Return for Revision	2014-10-01 17:25
Revised	2014-10-02 14:36
Second Decision	2014-10-29 17:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-29 18:45
Articles in Press	2014-10-29 18:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-22 16:29
Publish the Manuscript Online	2015-01-14 11:53

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Neuroimaging
Manuscript Type	Review
Article Title	In vivo imaging of endogenous neural stem cells in the adult brain
Manuscript Source	Invited Manuscript
All Author List	Maria Adele Rueger and Michael Schroeter
Funding Agency and Grant Number
Corresponding Author	Priv.-Doz. Dr. med. Maria Adele Rueger, Department of Neurology, University Hospital of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany. adele.rueger@uk-koeln.de
Key Words	Neural stem cells; Positron emission tomography; Magnetic resonance imaging; 3’-deoxy-3’-[18F]fluoro-L-thymidine; [11C]PK11195
Core Tip	Endogenous neural stem cells (eNSCs) in the adult mammalian brain can be mobilized by, e.g., pharmacological methods to facilitate regeneration and enhance functional recovery in neurological disease. In order to translate experimental approaches into the clinical setting, non-invasive imaging of eNSCs is required to monitor their fate in vivo. This review summarizes current imaging modalities suitable to monitor eNSCs in individual experimental animals over time, including optical imaging, magnetic resonance tomography and-spectroscopy, as well as Positron-Emission-Tomography, placing emphasis on the specificity of the signal obtained, as well as on their potential for clinical translation.
Publish Date	2015-01-14 11:53
Citation	Rueger MA, Schroeter M. In vivo imaging of endogenous neural stem cells in the adult brain. World J Stem Cells 2015; 7(1): 75-83
URL	http://www.wjgnet.com/1948-0210/full/v7/i1/75.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i1.75

Full Article (PDF)	WJSC-7-75.pdf
Full Article (Word)	WJSC-7-75.doc
Manuscript File	13418-Review.doc
Answering Reviewers	13418-Answering reviewers.pdf
Copyright License Agreement	13418-Copyright assignment.pdf
Peer-review Report	13418-Peer review(s).pdf
Scientific Misconduct Check	13418-CrossCheck.jpg
Scientific Editor Work List	13418-Scientific editor work list.pdf