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4/14/2015 6:13:00 PM | Browse: 1049 | Download: 1257
Publication Name World Journal of Hepatology
Manuscript ID 13479
Country/Territory Spain
Received
2014-08-25 08:21
Peer-Review Started
2014-08-25 17:06
To Make the First Decision
2014-11-27 12:25
Return for Revision
2014-12-02 14:54
Revised
2014-12-15 19:29
Second Decision
2015-01-08 16:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-01-19 13:30
Articles in Press
2015-01-19 13:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-03-29 13:02
Publish the Manuscript Online
2015-04-14 18:13
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Strategies to improve outcome of patients with hepatocellular carcinoma receiving a liver transplantation
Manuscript Source Invited Manuscript
All Author List Marta Guerrero-Misas, Manuel Rodríguez-Perálvarez and Manuel De la Mata
Funding Agency and Grant Number
Corresponding Author Manuel De la Mata, MD, PhD, Head, Department of Hepatology and Liver Transplantation, Reina Sofía University Hospital, Maimónides Institute of Biomedical Research of Córdoba, CIBERehd, Avda/ Menéndez Pidal s/n, 14004 Córdoba, Spain. mdelamatagarcia@gmail.com
Key Words Hepatocellular carcinoma; Recurrence; Bridging therapy; Milan criteria; Immunosuppression; Liver transplantation
Core Tip Liver transplantation is the only therapeutic option which allows to treat both, the hepatocellular carcinoma and the underlying liver disease. However, tumour recurrence rates are 15%-20% with a very poor prognosis. Strategies to minimize tumour recurrence and thus to improve outcome are focused in a careful selection of candidates for liver transplantation, an optimized management within waiting list and a tailored immunosuppression. The available scientific evidence supporting these strategies is reviewed, and future directions are provided for novel research approaches, which may contribute to the final target: to cure more patients with hepatocellular carcinoma with an improved long term outcome.
Publish Date 2015-04-14 18:13
Citation Guerrero-Misas M, Rodríguez-Perálvarez M, De la Mata M. Strategies to improve outcome of patients with hepatocellular carcinoma receiving a liver transplantation. World J Hepatol 2015; 7(4): 649-661
URL http://www.wjgnet.com/1948-5182/full/v7/i4/649.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i4.649
Full Article (PDF) WJH-7-649.pdf
Full Article (Word) WJH-7-649.doc
Manuscript File 13479-Review.docx
Answering Reviewers 13479-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 13479-Conflict-of-interest statement.pdf
Copyright License Agreement 13479-Copyright assignment.pdf
Peer-review Report 13479-Peer review(s).pdf
Scientific Misconduct Check 13479-CrossCheck.jpg
Scientific Editor Work List 13479-Scientific editor work list.pdf