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Articles Published Processes
4/15/2015 11:01:00 AM | Browse: 1146 | Download: 2400
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Received |
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2014-08-25 16:55 |
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Peer-Review Started |
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2014-08-26 14:24 |
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To Make the First Decision |
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2014-09-27 16:01 |
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Return for Revision |
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2014-10-10 13:47 |
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Revised |
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2014-11-19 14:43 |
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Second Decision |
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2014-12-26 13:41 |
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Accepted by Journal Editor-in-Chief |
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2014-12-27 10:14 |
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Accepted by Executive Editor-in-Chief |
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2015-01-08 17:20 |
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Articles in Press |
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2015-01-08 17:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-01-22 23:11 |
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Typeset the Manuscript |
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2015-03-31 19:48 |
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Publish the Manuscript Online |
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2015-04-15 11:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Prophylactic antiviral therapy in allogeneic hematopoietic stem cell transplantation in hepatitis B virus patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Ping Liao, Jia-Lu Jiang, Wai-Yi Zou, Duo-Rong Xu and Juan Li |
| Funding Agency and Grant Number |
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| Corresponding Author |
Wai-Yi Zou, Associate Professor, Department of Hematology, the First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510000, Guangdong Province, China. waiyizou@medmail.com.cn |
| Key Words |
Hematopoietic stem cell transplantation; Hepatitis B virus; Antiviral therapy; Nucleotide analogues |
| Core Tip |
The threshold of pre-transplantation hepatitis B virus (HBV) DNA for allo-HSCT was defined as 103 IU/mL. Only 1 patient developed HBV reactivation due to early discontinuation of antiviral therapy. The hepatitis B surface antigen (HBsAg)(+), HBsAg(-)/hepatitis B core antibody(+) and non-HBV infected groups showed no statistically significant differences in the incidence of graft-vs-host disease, drug-induced liver injury, hepatic veno-occlusive disease death, survival times and post-transplantation cumulative survival rates. In summary, suppression of HBV DNA to < 103 IU/mL before transplantation, continued antiviral therapy and close monitoring of immune markers of hepatitis B and HBV DNA after trans plantation may assure the safety of allogeneic hematopoietic stem cell transplantation. |
| Publish Date |
2015-04-15 11:01 |
| Citation |
Liao YP, Jiang JL, Zou WY, Xu DR, Li J. Prophylactic antiviral therapy in allogeneic hematopoietic stem cell transplantation in hepatitis B virus patients. World J Gastroenterol 2015; 21(14): 4284-4292 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i14/4284.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i14.4284 |
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