Publication Name	World Journal of Diabetes
Manuscript ID	13507
Country	United Kingdom

Received	2014-08-26 09:11
Peer-Review Started	2014-08-26 17:29
To Make the First Decision	2014-09-16 10:55
Return for Revision	2014-09-19 11:59
Revised	2014-10-03 16:40
Second Decision	2014-10-27 16:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-27 17:16
Articles in Press	2014-10-27 17:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-23 16:08
Publish the Manuscript Online	2014-12-13 19:01

ISSN	1948-9358 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Biomarkers in diabetic nephropathy: Present and future
Manuscript Source	Invited Manuscript
All Author List	Gemma Currie, Gerard McKay and Christian Delles
Funding Agency and Grant Number
Corresponding Author	Dr. Gemma Currie, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, G12 8TA Glasgow, United Kingdom. gemma.currie@glasgow.ac.uk
Key Words	Diabetes; Nephropathy; Microalbuminuria; Proteinuria; Biomarkers
Core Tip	Microalbuminuria (MA) is the earliest and most commonly used clinical index of diabetic nephropathy (DN), however its sensitivity and specificity for early disease detection are limited. Not all patients with MA progress to overt DN, nonalbuminuric DN is common and risk associated with MA is elevated even at levels below currently accepted diagnostic thresholds. There is therefore a need for alternative biomarkers allowing early identification of “at risk” individuals. This review focusses on biomarkers of glomerular and tubular dysfunction, oxidative stress and inflammation that have attracted interest. In addition we review more novel strategies including proteomic, metabolomic and genomic approaches.
Publish Date	2014-12-13 19:01
Citation	Currie G, McKay G, Delles C. Biomarkers in diabetic nephropathy: Present and future. World J Diabetes 2014; 5(6): 763-776
URL	http://www.wjgnet.com/1948-9358/full/v5/i6/763.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i6.763

Full Article (PDF)	WJD-5-763.pdf
Full Article (Word)	WJD-5-763.doc
Manuscript File	13507-Review.docx
Answering Reviewers	13507-Answering reviewers.pdf
Copyright License Agreement	13507-Copyright assignment.pdf
Peer-review Report	13507-Peer review(s).pdf
Scientific Misconduct Check	13507-CrossCheck.jpg
Scientific Editor Work List	13507-Scientific editor work list.pdf