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6/3/2015 12:01:00 PM | Browse: 328 | Download: 488
Publication Name World Journal of Hepatology
Manuscript ID 13540
Country of Manuscript Source Taiwan
2014-08-27 08:54
Peer-Review Started
2014-08-27 14:26
To Make the First Decision
2014-09-28 12:26
Return for Revision
2014-09-30 14:52
2014-11-29 11:02
Second Decision
2015-03-16 17:43
Accepted by Journal Editor-in-Chief
2015-03-17 04:30
Accepted by Company Editor-in-Chief
2015-04-02 16:04
Articles in Press
2015-04-02 16:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-04-05 13:26
Typeset the Manuscript
2015-05-18 18:00
Publish the Manuscript Online
2015-06-03 12:00
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Current systemic treatment of hepatocellular carcinoma: A review of the literature
Manuscript Source Invited Manuscript
All Author List Kai-Wen Chen, Tzu-Ming Ou, Chin-Wen Hsu, Chi-Ting Horng, Ching-Chang Lee, Yuh-Yuan Tsai, Chi-Chang Tsai, Yi-Sheng Liou, Chen-Chieh Yang, Chao-Wen Hsueh and Wu-Hsien Kuo
Funding Agency and Grant Number
Correspondence To Wu-Hsien Kuo, MD, PhD, Professor, Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital, No.2, Zhongzheng 1st Rd., Lingya District, Kaohsiung 80284, Taiwan. wuhsienku@gmail.com
Keywords Hepatocellular carcinoma; Transarterial chemoembolization; Sorafenib; Systemic treatment; Molecular target therapy
Core Tip Sorafenib is a multi-targeted tyrosine kinase inhibitor that was the first systemic therapy in the world to improve the survival rate of patients with advanced hepatocellular carcinoma (HCC) in a phase Ⅲ trial. However, the overall outcomes are sometimes unsatis-factory and there is a need for second line therapies in patients with advanced HCC who still progress after the use of sorafenib. Novel systemic approaches are needed in advanced HCC.
Publish Date 2015-06-03 12:00
Citation Chen KW, Ou TM, Hsu CW, Horng CT, Lee CC, Tsai YY, Tsai CC, Liou YS, Yang CC, Hsueh CW, Kuo WH. Current systemic treatment of hepatocellular carcinoma: A review of the literature. World J Hepatol 2015; 7(10): 1412-1420
Url http://www.wjgnet.com/1948-5182/full/v7/i10/1412.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i10.1412
Full Article (PDF) WJH-7-1412.pdf
Full Article (Word) WJH-7-1412.doc
Revised Manuscript 13540-Review.doc
Peer-review Report 13540-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 13540-Journal editor-in-chief review report.pdf
Answering Reviewers 13540-Answering reviewers.pdf
Scientific Misconduct Check 13540-Scientific misconduct check.pdf
Scientific Editor Work List 13540-Scientific editor work list.pdf
Conflict-of-Interest Disclosure Form 13540-Conflict-of-interest statement.pdf
Copyright License Agreement 13540-Copyright assignment.pdf