Publication Name	World Journal of Hepatology
Manuscript ID	13589
Country	Netherlands

Received	2014-08-28 09:11
Peer-Review Started	2014-08-31 19:53
To Make the First Decision	2014-09-28 13:56
Return for Revision	2014-09-29 20:18
Revised	2014-10-22 00:00
Second Decision	2014-10-30 16:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-11-10 16:10
Articles in Press	2014-11-10 16:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-27 19:08
Publish the Manuscript Online	2015-01-10 16:31

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees
Manuscript Source	Invited Manuscript
All Author List	Babs E Verstrepen, André Boonstra and Gerrit Koopman
Funding Agency and Grant Number	Funding Agency Grant Number Fifth framework program from the EU (in part) BIO-CT98-0357 Fifth framework program from the EU (in part) QLK2-CT-1999-00356 Fifth framework program from the EU (in part) ERC-2008-AdG-233130-HEPCENT (to Verstrepen BE) Dutch government project FES0908 (to Boonstra A)
Corresponding Author	Gerrit Koopman, PhD, Department of Virology, Biomedical Primate Research Centre, PO Box 3306, 2280GH Rijswijk, The Netherlands. koopman@bprc.nl
Key Words	Hepatitis C virus; Vaccines; Chimpanzees; Review; Prophylactic; Antibodies; T-cells
Core Tip	With the near disappearance of the most relevant animal model for hepatitis C virus (HCV), the chimpanzee, we review the progression that has been made regarding vaccine development against this virus infection. An estimated 3 million people suffering from chronic hepatitis caused by HCV die each year. Currently, there is no approved vaccine available to prevent new infection.
Publish Date	2015-01-10 16:31
Citation	Verstrepen BE, Boonstra A, Koopman G. Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees. World J Hepatol 2015; 7(1): 53-69
URL	http://www.wjgnet.com/1948-5182/full/v7/i1/53.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i1.53

Full Article (PDF)	WJH-7-53.pdf
Full Article (Word)	WJH-7-53.doc
Manuscript File	13589-Review.docx
Answering Reviewers	13589-Answering reviewers.pdf
Copyright License Agreement	13589-Copyright assignment.pdf
Peer-review Report	13589-Peer review(s).pdf
Scientific Misconduct Check	13589-CrossCheck.jpg
Scientific Editor Work List	13589-Scientific editor work list.pdf