Publication Name	World Journal of Gastroenterology
Manuscript ID	136
Country	Poland

Received	2012-08-03 00:55
Peer-Review Started	2012-09-04 11:14
First Decision by Editorial Office Director
Return for Revision	2012-12-14 16:22
Revised	2013-03-04 19:32
Publication Fee Transferred
Second Decision by Editor	2013-03-15 18:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-03-15 23:15
Articles in Press
Edit the Manuscript by Language Editor	2013-06-27 16:04
Typeset the Manuscript	2013-07-09 09:39
Publish the Manuscript Online	2013-07-20 20:47

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Autobiography
Article Title	Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylation
Manuscript Source	Invited Manuscript
All Author List	Piotr M Wierzbicki, Krystian Adrych, Dorota Kartanowicz, Marcin Stanislawowski, Anna Kowalczyk, Janusz Godlewski, Iwona Skwierz-Bogdanska, Krzysztof Celinski, Tomasz Gach, Jan Kulig, Bartlomiej Korybalski and Zbigniew Kmiec
Funding Agency and Grant Number	Funding Agency Grant Number Polish Ministry of Science N N402 683940
Corresponding Author	Dr. Piotr M Wierzbicki, Department of Histology, Faculty of Medicine, Medical University of Gdansk, 1 Debinki Str., 80210 Gdansk, Poland. pwierzb@gumed.edu.pl
Key Words	Large tumor suppressor 1; Colorectal cancer; Quantitative polymerase chain reaction; Reduced expression; Promoter hypermethylation; Microsatellite instability; Salvador-Warts-Hippo pathway
Core Tip	Searching for new colorectal cancer (CRC) molecular markers is a very important objective, because CRC is one of the most common malignancies in the world and one of the most fatal of human neoplasms. Decreased expression of large tumor suppressor 1 in CRC was associated with promoter hypermethylation, but not microsatellite instability status. Such reduced expression may promote progression of CRC.
Publish Date	2013-07-20 20:47
Citation	Wierzbicki PM, Adrych K, Kartanowicz D, Stanislawowski M, Kowalczyk A, Godlewski J, Skwierz-Bogdanska I, Celinski K, Gach T, Kulig J, Korybalski B, Kmiec Z. Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylation. World J Gastroenterol 2013; 19(27): 4363-4373
URL	http://www.wjgnet.com/1007-9327/full/v19/i27/4363.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i27.4363

Full Article (PDF)	WJG-19-4363.pdf
Manuscript File	136-Review.doc
Answering Reviewers	136-Answering reviewers.pdf
Copyright License Agreement	136-Copyright assignment.pdf
Peer-review Report	136-Peer review.docx
Scientific Editor Work List	136-Scientific editor work list.doc