Publication Name	World Journal of Hepatology
Manuscript ID	13611
Country	Egypt

Received	2014-08-28 08:08
Peer-Review Started	2014-08-29 08:21
To Make the First Decision	2014-10-14 18:09
Return for Revision	2014-10-20 17:36
Revised	2014-10-26 01:08
Second Decision	2015-03-24 17:02
Accepted by Journal Editor-in-Chief	2015-03-25 17:01
Accepted by Executive Editor-in-Chief	2015-04-07 16:25
Articles in Press	2015-04-07 16:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-15 09:19
Publish the Manuscript Online	2015-06-03 12:00

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Liver transplantation as a management of hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Ayman Zaki Azzam
Funding Agency and Grant Number
Corresponding Author	Ayman Zaki Azzam, MD, PhD, Department of General Surgery, Faculty of Medicine, Alexandria University, 22 Al-Guish Avenue, Alexandria 21526, Egypt. aazzam70@yahoo.com
Key Words	Hepatocellular carcinoma; Management; Liver transplantation; Pretransplant adjuvant therapy; Milan criteria
Core Tip	Hepatocellular carcinoma (HCC) has a poor prognosis if untreated. Screening is challenging due to the lack of specific biomarkers. Successful screening is very important as early diagnosis can provide curative opportunities. Orthotopic liver transplantation (LT) is the best therapeutic option for early, unresectable HCC. When transplantation occurs within the established Milan criteria, the outcomes are good. The shortage of organs from deceased donors led to the adoption of extended criteria. Several measures have been taken to solve these problems including prioritization of patients with HCC, use of pretransplant adjuvant treatment, and living donor LT.
Publish Date	2015-06-03 12:00
Citation	Azzam AZ. Liver transplantation as a management of hepato­cellular carcinoma. World J Hepatol 2015; 7(10): 1347-1354
URL	http://www.wjgnet.com/1948-5182/full/v7/i10/1347.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i10.1347

Full Article (PDF)	WJH-7-1347.pdf
Full Article (Word)	WJH-7-1347.doc
Manuscript File	13611-Review.doc
Answering Reviewers	13611-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13611-Conflict-of-interest statement.pdf
Copyright License Agreement	13611-Copyright assignment.PDF
Peer-review Report	13611-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	13611-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	13611-Scientific misconduct check.pdf
Scientific Editor Work List	13611-Scientific editor work list.pdf