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6/3/2015 12:01:00 PM | Browse: 1170 | Download: 1665
Publication Name World Journal of Hepatology
Manuscript ID 13633
Country/Territory China
Received
2014-08-28 17:56
Peer-Review Started
2014-08-28 19:16
To Make the First Decision
2014-10-14 18:08
Return for Revision
2014-10-20 17:16
Revised
2014-11-08 12:31
Second Decision
2015-04-01 14:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-04-07 16:26
Articles in Press
2015-04-07 16:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-05-18 13:47
Publish the Manuscript Online
2015-06-03 12:00
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Review
Article Title Chemokines and their receptors play important roles in the development of hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Chun-Min Liang, Long Chen, Heng Hu, Hui-Ying Ma, Ling-Ling Gao, Jie Qin and Cui-Ping Zhong
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Foundation of China 31471147
Corresponding Author Chun-Min Liang, MD, PhD, Lab of Tumor Immunology, Department of Anatomy and Histology and Embryology, Shanghai Medical College of Fudan University, 138 Yixueyuan Road, Shanghai 200032, China. cmliang@fudan.edu.cn
Key Words Chemokines; Hepatocellular carcinoma; Immune cells; Chemokine receptors; Inflammation; Angiogenesis; Tumor behaviors; Treatments
Core Tip The chemokine system not only serves as the core components in orchestrating the normal immune response but also plays a key role in the microenvironment of hepatocellular carcinoma (HCC). Therefore, the thorough understanding of its role is indispensible for devising effective treatments. During the progress of HCC, the chemokine system boosts aberrant inflammation and angiogenesis through simultaneously affecting different kinds of immune cells and influencing the migration, invasion, growth and survival of tumor cells. Targeting the chemokine system has elicited powerful anti-tumor effects and this indicates an encouraging treatment option in HCC.
Publish Date 2015-06-03 12:00
Citation Liang CM, Chen L, Hu H, Ma HY, Gao LL, Qin J, Zhong CP. Chemokines and their receptors play important roles in the development of hepatocellular carcinoma. World J Hepatol 2015; 7(10): 1390-1402
URL http://www.wjgnet.com/1948-5182/full/v7/i10/1390.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i10.1390
Full Article (PDF) WJH-7-1390.pdf
Full Article (Word) WJH-7-1390.doc
Manuscript File 13633-Review.docx
Answering Reviewers 13633-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 13633-Conflict-of-interest statement.pdf
Copyright License Agreement 13633-Copyright assignment.pdf
Peer-review Report 13633-Peer-review(s).pdf
Scientific Misconduct Check 13633-Scientific misconduct check.pdf
Scientific Editor Work List 13633-Scientific editor work list.pdf