Publication Name	World Journal of Diabetes
Manuscript ID	13674
Country	Brazil

Received	2014-08-29 10:22
Peer-Review Started	2014-08-30 13:18
To Make the First Decision	2014-11-14 19:52
Return for Revision	2014-11-18 19:01
Revised	2014-11-26 01:18
Second Decision	2015-01-28 12:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-02-09 09:39
Articles in Press	2015-02-09 09:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-07 14:00
Publish the Manuscript Online	2015-04-20 09:13

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Diabetic neuropathic pain: Physiopathology and treatment
Manuscript Source	Invited Manuscript
All Author List	Anne K Schreiber, Carina FM Nones, Renata C Reis, Juliana G Chichorro and Joice M Cunha
Funding Agency and Grant Number
Corresponding Author	Dr. Joice M Cunha, Professor, Department of Pharmacology, Biological Sciences Sector, Federal University of Parana, Rua XV de Novembro, 1299 - Centro, Curitiba 81540-970, Brazil. joice.cunha@ufpr.br
Key Words	Diabetes; Neuropathic pain; Hyperglycemia; Anticonvulsants; Antidepressants
Core Tip	Diabetic neuropathic pain is a common complication of diabetes and the most common form of neuropathic pain. In this review, we will discuss the various factors that may contribute to the pathogenesis of diabetic neuropathic pain, including metabolic, vascular, autoimmune and oxidative stress-related mechanisms. In addition, we will review the possibilities of pain treatment, taken into consideration the first line drugs clinically used, the antidepressants and anticonvulsants, but also other options such as opioids, tapentadol and drugs for topical use, such as lidocaine and capsaicin cream.
Publish Date	2015-04-20 09:13
Citation	Schreiber AK, Nones CFM, Reis RC, Chichorro JG, Cunha JM. Diabetic neuropathic pain: Physiopathology and treatment. World J Diabetes 2015; 6(3): 432-444
URL	http://www.wjgnet.com/1948-9358/full/v6/i3/432.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i3.432

Full Article (PDF)	WJD-6-432.pdf
Full Article (Word)	WJD-6-432.doc
Manuscript File	13674-Review.doc
Answering Reviewers	13674-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13674-Conflict-of-interest statement.pdf
Copyright License Agreement	13674-Copyright assignment.pdf
Peer-review Report	13674-Peer-review(s).pdf
Scientific Misconduct Check	13674-Scientific misconduct check.pdf
Scientific Editor Work List	13674-Scientific editor work list.pdf