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Articles Published Processes
6/29/2015 5:40:00 PM | Browse: 936 | Download: 1760
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Received |
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2014-08-29 09:48 |
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Peer-Review Started |
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2014-08-30 13:38 |
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To Make the First Decision |
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2014-12-17 11:37 |
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Return for Revision |
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2014-12-19 11:02 |
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Revised |
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2015-01-15 20:08 |
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Second Decision |
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2015-04-15 17:52 |
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Accepted by Journal Editor-in-Chief |
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2015-04-15 20:21 |
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Accepted by Executive Editor-in-Chief |
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2015-05-28 18:06 |
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Articles in Press |
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2015-05-28 18:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-06-04 05:24 |
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Typeset the Manuscript |
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2015-06-09 14:33 |
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Publish the Manuscript Online |
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2015-06-29 17:40 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Virology |
Manuscript Type |
Minireviews |
Article Title |
Induced immunity against hepatitis B virus
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Manuscript Source |
Invited Manuscript |
All Author List |
Zeinab Nabil Ahmed Said and Kouka Saadeldin Abdelwahab |
Funding Agency and Grant Number |
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Corresponding Author |
Zeinab Nabil Ahmed Said, Professor, Department of Microbiology and Immunology, Faculty of Medicine (for girls), Al-Azhar University, Nasr City, Cairo 11754, Egypt. znabil58@yahoo.com
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Key Words |
Hepatitis B surface antigen; Hepatitis B virus vaccines; Immunological memory; Hepatitis B virus; Booster and therapeutic vaccination |
Core Tip |
Worldwide, it is estimated that more than 2 billion people have been infected with hepatitis B virus (HBV). Of these, approximately 240 million are chronically infected and at risk of serious illness or death from development of cirrhosis and subsequent progression to hepatocellular carcinoma (HCC), estimated to cause one million deaths each year worldwide. Prevention and control of HBV infection can therefore make a significant contribution to community health and to saving lives by preventing HCC. This review concerns the major advances in the field of HBV over the last few decades which have resulted in understanding the natural history of HBV infection and the development of effective vaccines against the virus. In the era of universal HBV vaccination coverage, the current growing body of knowledge regarding monitoring and surveillance of HBV vaccination programs and the policy of booster vaccination, several issues have to be evaluated re-garding the vaccination policy and booster doses. In addition, it is worth evaluating vaccine-escape viral mutants, long-term protection and the therapeutic use of HBV vaccine as a promising new strategy for controlling chronic HBV infection.
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Publish Date |
2015-06-29 17:40 |
Citation |
Said ZNA, Abdelwahab KS. Induced immunity against hepatitis B virus. World J Hepatol 2015; 7(12): 1660-1670 |
URL |
http://www.wjgnet.com/1948-5182/full/v7/i12/1660.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v7.i12.1660 |
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