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Articles Published Processes
12/2/2015 11:59:00 AM | Browse: 1007 | Download: 857
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Received |
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2014-08-29 08:11 |
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Peer-Review Started |
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2014-08-29 17:07 |
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To Make the First Decision |
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2014-10-14 18:03 |
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Return for Revision |
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2014-10-20 16:26 |
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Revised |
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2014-11-06 01:53 |
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Second Decision |
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2015-01-29 09:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-02-09 10:41 |
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Articles in Press |
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2015-02-09 10:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-04-13 14:08 |
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Publish the Manuscript Online |
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2015-05-15 19:54 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Minireviews |
Article Title |
Lean diabetes mellitus: An emerging entity in the era of obesity
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Manuscript Source |
Invited Manuscript |
All Author List |
Amrutha Mary George, Amith George Jacob and Leon Fogelfeld |
Funding Agency and Grant Number |
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Corresponding Author |
Leon Fogelfeld, MD, Head Division of Endocrinology, John H Stroger Hospital of Cook County, Professor of Medicine, Rush University Medical Center, Division of Endocrinology, John H Stroger Hospital of Cook County, 1901 W Harrison Street, W.Polk (room 811), Chicago, IL 60612, United States. lfogelfe@cchil.org
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Key Words |
Lean diabetes; Beta cell failure; Ketosis resistant diabetes of young; Obesity paradox; Sarcopenic obesity |
Core Tip |
Little is known about lean diabetes (pati-ents with low-normal body mass index). Studies in developing countries have shown that these patients have history of childhood malnutrition, poor socioeconomic status and early age of onset with absence of ketosis. In the United States, recent studies showed that the lean, normal weight diabetes is not rare especially among minorities. These patients are mainly males and have higher prevalence of insulin use indicating rapid beta cell failure. They might have increased total, cardiovascular and non cardiovascular mortality when compared to obese diabetic patients. The potential causal mechanisms of this diabetes type may include genetic, acquired and behavioral factors.
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Publish Date |
2015-05-15 19:54 |
Citation |
George AM, Jacob AG, Fogelfeld L. Lean diabetes mellitus: An emerging entity in the era of obesity. World J Diabetes 2015; 6(4): 613-620 |
URL |
http://www.wjgnet.com/1948-9358/full/v6/i4/613.htm |
DOI |
http://dx.doi.org/10.4239/wjd.v6.i4.613 |
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