Publication Name	World Journal of Hepatology
Manuscript ID	13744
Country	Argentina

Received	2014-08-30 12:59
Peer-Review Started	2014-08-30 13:06
First Decision by Editorial Office Director
Return for Revision	2014-11-01 15:36
Revised	2014-11-05 21:08
Publication Fee Transferred
Second Decision by Editor	2015-01-14 08:25
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2015-01-20 16:47
Articles in Press	2015-01-20 16:47
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-26 10:34
Publish the Manuscript Online	2015-04-14 18:13

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Pre-treatment prediction of response to peginterferon plus ribavirin in chronic hepatitis C genotype 3
Manuscript Source	Invited Manuscript
All Author List	Sebastián Marciano, Silvia M Borzi, Melisa Dirchwolf, Ezequiel Ridruejo, Manuel Mendizabal, Fernando Bessone, María E Sirotinsky, Diego H Giunta, Julieta Trinks, Pablo A Olivera, Omar A Galdame, Marcelo O Silva, Hugo A Fainboim and Adrián C Gadano
Funding Agency and Grant Number
Corresponding Author	Sebastián Marciano, MD, Liver Unit, Hospital Italiano de Buenos Aires, Juan D. Peron 4190, C1181ACH Capital Federal, Buenos Aires, Argentina. sebastian.marciano@hospitalitaliano.org.ar
Key Words	Sustained virological response; Direct antiviral agents; Sofosbuvir; Cirrhosis; Viral load
Core Tip	Our study evaluates pre-treatment factors associated with sustained virological response in patients with hepatitis C virus genotype 3 treated with peginterferon plus ribavirin. We identified a sub-group of patients with high pre-treatment viral load and advanced fibrosis whose chance of achieving a sustained virological response is as low as 29%. We believe these patients should be prioritized to access new treatment strategies.
Publish Date	2015-04-14 18:13
Citation	Marciano S, Borzi SM, Dirchwolf M, Ridruejo E, Mendizabal M, Bessone F, Sirotinsky ME, Giunta DH, Trinks J, Olivera PA, Galdame OA, Silva MO, Fainboim HA, Gadano AC. Pre-treatment prediction of response to peginterferon plus ribavirin in chronic hepatitis C genotype 3. World J Hepatol 2015; 7(4): 703-709
URL	http://www.wjgnet.com/1948-5182/full/v7/i4/703.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i4.703

Full Article (PDF)	WJH-7-703.pdf
Full Article (Word)	WJH-7-703.doc
Manuscript File	13744-Review.docx
Answering Reviewers	13744-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13744-Conflict-of-interest statement.pdf
Copyright License Agreement	13744-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	13744-Institutional review board statement.pdf
Peer-review Report	13744-Peer review(s).pdf
Scientific Misconduct Check	13744-CrossCheck.jpg
Scientific Editor Work List	13744-Scientific editor work list.pdf