Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	13846
Country	United States

Received	2014-09-04 08:49
Peer-Review Started	2014-09-04 11:13
To Make the First Decision	2015-01-08 14:03
Return for Revision	2015-01-10 20:32
Revised	2015-01-27 10:20
Second Decision	2015-03-16 17:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-02 16:13
Articles in Press	2015-04-02 16:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-16 14:03
Publish the Manuscript Online	2015-07-08 09:21

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Feasibility and safety of endoscopic cryoablation at the duodenal papilla: Porcine model
Manuscript Source	Unsolicited Manuscript
All Author List	Dennis Yang, Mary K Reinhard and Mihir S Wagh
Funding Agency and Grant Number
Corresponding Author	Mihir S Wagh, MD, FASGE, Division of Gastroenterology, University of Florida, 1329 SW 16th Street, Room 5251, Gainesville, FL 32608, United States. mihir.wagh@medicine.ufl.edu
Key Words	Liquid-nitrogen cryotherapy; Cryoablation; Duodenal adenoma; Ampullectomy; Papillectomy
Core Tip	With advances in therapeutic endoscopy, endoscopic resection is commonly performed for the management of ampullary adenomas. However, endoscopic papillectomy can still carry significant morbidity, especially in elderly patients with comorbi-dities. Hence, less invasive effective endoscopic ablative modalities would be desirable. In this study, we demonstrate that endoscopic liquid nitrogen spray cryotherapy is feasible and safe for ablation at the duodenal papilla in a porcine model. These preliminary findings suggest a potential role of cryotherapy as an adjunct endoscopic treatment for residual/recurrent ampullary lesions or as a primary modality in patients who are not optimal candidates for surgery or endo-scopic resection.
Publish Date	2015-07-08 09:21
Citation	Yang D, Reinhard MK, Wagh MS. Feasibility and safety of endoscopic cryoablation at the duodenal papilla: Porcine model. World J Gastrointest Endosc 2015; 7(7): 728-735
URL	http://www.wjgnet.com/1948-5190/full/v7/i7/728.htm
DOI	http://dx.doi.org/10.4253/wjge.v7.i7.728

Full Article (PDF)	WJGE-7-728.pdf
Full Article (Word)	WJGE-7-728.doc
Manuscript File	13846-Review.doc
Answering Reviewers	13846-Answering reviewers.pdf
Audio Core Tip	13846-Audio core tip.m4a
Biostatistics Review Certificate	13846-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	13846-Conflict-of-interest statement.pdf
Copyright License Agreement	13846-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	13846-Institutional review board statement.pdf
Scientific Misconduct Check	13846-Scientific misconduct check.pdf
Scientific Editor Work List	13846-Scientific editor work list.pdf