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3/16/2015 6:04:00 PM | Browse: 1160 | Download: 1343
Publication Name World Journal of Gastroenterology
Manuscript ID 13870
Country/Territory China
Received
2014-09-05 08:24
Peer-Review Started
2014-09-05 17:52
To Make the First Decision
2014-09-27 16:16
Return for Revision
2014-09-30 15:56
Revised
2014-10-10 22:13
Second Decision
2014-11-24 11:56
Accepted by Journal Editor-in-Chief
2014-11-25 19:26
Accepted by Company Editor-in-Chief
2014-12-08 16:37
Articles in Press
2014-12-08 17:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-12-16 20:53
Typeset the Manuscript
2015-03-04 12:03
Publish the Manuscript Online
2015-03-16 18:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Increased VGLUT3 involved in visceral hyperalgesia in a rat model of irritable bowel syndrome
Manuscript Source Unsolicited Manuscript
All Author List Chang-Qing Yang, Li-Ping Duan, Pei-Tang Qiao, Li Zhao and Li-Li Guo
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 30940033
Doctoral Program of Higher Education of China
Corresponding Author Chang-Qing Yang, PhD, Department of Gastroenterology, Peace Hospital, Changzhi Medical College, 110 South Yan-an Rd., Changzhi 046000, Shanxi Province, China. yangchangqing111@sohu.com
Key Words Vesicular glutamate transporter-3; Irritable bowel syndrome; Mast cell; Infection; Stress; Neuron
Core Tip It has been shown that visceral hyperalgesia in response to various stimuli from the gut of irritable bowel syndrome (IBS) patients is an important factor in abdominal pain. Our research indicated that the vesicular glutamate transporter 3 (VGLUT3), which concentrates the excitatory neurotransmitter glutamate into synaptic vesicles in peripheral and central neurons, is involved in the pathogenesis of visceral hyperalgesia. An infection-induced increase in VGLUT3 may be one of the main reasons for visceral hyperalgesia in IBS patients.
Publish Date 2015-03-16 18:04
Citation Yang CQ, Duan LP, Qiao PT, Zhao L, Guo LL. Increased VGLUT3 involved in visceral hyperalgesia in a rat model of irritable bowel syndrome. World J Gastroenterol 2015; 21(10): 2959-2966
URL http://www.wjgnet.com/1007-9327/full/v21/i10/2959.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i10.2959
Full Article (PDF) WJG-21-2959.pdf
Full Article (Word) WJG-21-2959.doc
Manuscript File 13870-Review.doc
Answering Reviewers 13870-Answering reviewers.pdf
Copyright License Agreement 13870-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 13870-Language certificate.pdf
Peer-review Report 13870-Peer review(s).pdf
Scientific Misconduct Check 13870-CrossCheck.jpg
Scientific Editor Work List 13870-Scientific editor work list.pdf