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5/19/2015 5:28:00 PM | Browse: 594 | Download: 785
Publication Name World Journal of Hepatology
Manuscript ID 13888
Country of Manuscript Source China
Received
2014-09-05 18:05
Peer-Review Started
2014-09-06 12:07
To Make the First Decision
2015-01-08 14:11
Return for Revision
2015-01-13 14:09
Revised
2015-01-27 20:42
Second Decision
2015-02-10 16:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-02-12 14:46
Articles in Press
2015-02-12 14:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-05-04 10:49
Publish the Manuscript Online
2015-05-19 17:28
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Minireviews
Article Title Management of recurrent hepatocellular carcinoma after liver transplant
Manuscript Source Invited Manuscript
All Author List Kenneth SH Chok
Funding Agency and Grant Number
Correspondence To Kenneth SH Chok, MBBS, Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China. kennethchok@gmail.com
Keywords Hepatocellular carcinoma; Recurrence; Transarterial chemoembolization; Liver transplantation; Targeted therapy; Resection; Radiofrequency ablation; Transarterial radioembolization; Immunosuppression; Stereotactic body radiation therapy
Core Tip The management of recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) seems to be a losing battle. Nonetheless, tremendous efforts have been made to combat this deadly disease. Intrahepatic recurrence may be treated by resection, which has some survival benefits as shown by small clinical trials. Other kinds of therapy including high-intensity focused ultrasound (HIFU) ablation, radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) are also in use. HIFU ablation has been shown to produce better results when compared with RFA and TACE. The efficacy of systemic and targeted therapies for multiple recurrences is under investigation. Early results have suggested that the combination of sorafenib with mammalian target of rapamycin inhibitors may be useful for treating recurrent HCC after LT.
Publish Date 2015-05-19 17:28
Citation Chok KSH. Management of recurrent hepatocellular carcinoma after liver transplant. World J Hepatol 2015; 7(8): 1142-1148
Url http://www.wjgnet.com/1948-5182/full/v7/i8/1142.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i8.1142
Full Article (PDF) WJH-7-1142.pdf
Full Article (Word) WJH-7-1142.doc
Manuscript File 13888-Review.doc
Answering Reviewers 13888-Answering reviewers.pdf
Audio Core Tip 13888-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 13888-Conflict-of-interest statement.pdf
Copyright License Agreement 13888-Copyright assignment.pdf
Peer-review Report 13888-Peer-review(s).pdf
Scientific Misconduct Check 13888-Scientific misconduct check.pdf
Scientific Editor Work List 13888-Scientific editor work list.pdf