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Articles Published Processes
3/9/2015 3:58:00 PM | Browse: 999 | Download: 1194
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Received |
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2014-09-06 11:36 |
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Peer-Review Started |
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2014-09-07 18:51 |
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To Make the First Decision |
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2014-10-14 16:50 |
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Return for Revision |
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2014-10-20 09:43 |
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Revised |
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2014-11-02 21:17 |
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Second Decision |
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2014-11-24 11:57 |
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Accepted by Journal Editor-in-Chief |
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2014-11-25 02:38 |
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Accepted by Executive Editor-in-Chief |
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2014-12-08 16:38 |
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Articles in Press |
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2014-12-08 17:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-12-17 18:12 |
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Typeset the Manuscript |
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2015-02-11 09:51 |
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Publish the Manuscript Online |
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2015-03-09 15:58 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Research & Experimental Medicine |
Manuscript Type |
Basic Study |
Article Title |
Are gastric mucosal macrophages responsible for gastric injury in acute pancreatitis?
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Sheng-Chun Dang, Hao Wang, Jian-Xin Zhang, Lei Cui, De-Li Jiang, Rong-Fang Chen, Jian-Guo Qu, Xiang-Qian Shen, Min Chen and Min Gu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Jiangsu Planned Projects for Postdoctoral Research Funds |
1302096B |
Natural Science Foundation of Jiangsu Province |
BK2011484 |
Natural Science Foundation of Jiangsu Province |
2012704 |
National Natural Science Foundation of China |
81070287 |
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Corresponding Author |
Sheng-Chun Dang, MD, Department of General Surgery, the Affiliated Hospital of Jiangsu University, No. 438 Jiefang Road, Zhenjiang 212001, Jiangsu Province, China. dscgu@163.com |
Key Words |
Pancreatitis; Clodronate disodium; Macrophage; Gastric mucosal injury |
Core Tip |
In this study, we investigated the protective effect of clodronate liposomes against severe acute pancreatitis (SAP)-triggered acute gastric mucosal injury in rats. Our results revealed that gastric macrophages are involved in the pathogenesis of gastric injury in SAP. Moreover, clodronate-containing liposomes have protective effects against gastric mucosal injury in rats with SAP. Therefore, the blockade of macrophage infiltration may represent a novel therapeutic strategy for the treatment of SAP. |
Publish Date |
2015-03-09 15:58 |
Citation |
Dang SC, Wang H, Zhang JX, Cui L, Jiang DL, Chen RF, Qu JG, Shen XQ, Chen M, Gu M. Are gastric mucosal macrophages responsible for gastric injury in acute pancreatitis? World J Gastroenterol 2015; 21(9): 2651-2657 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i9/2651.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i9.2651 |
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