Publication Name	World Journal of Hepatology
Manuscript ID	14034
Country	Australia

Received	2014-09-16 09:18
Peer-Review Started	2014-09-20 13:25
To Make the First Decision	2014-11-14 19:51
Return for Revision	2014-11-19 15:48
Revised	2014-12-04 03:55
Second Decision	2014-12-26 08:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-31 13:23
Articles in Press	2014-12-31 13:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-23 11:13
Publish the Manuscript Online	2015-03-31 15:58

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Topic Highlights
Article Title	Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance
Manuscript Source	Invited Manuscript
All Author List	Catherine MN Croagh, Paul V Desmond and Sally J Bell
Funding Agency and Grant Number
Corresponding Author	Dr. Catherine MN Croagh, Department of Gastroenterology, St Vincent’s Hospital, Level 4, Daly Wing, 35 Victoria Parade, Fitzroy, Victoria 3065, Australia. catherine.croagh@svha.org.au
Key Words	Chronic hepatitis B; Genotype; Pre-core; Basal core promotor; Mutations
Core Tip	Chronic hepatitis B (CHB) is a major global cause of liver related morbidity and mortality. Genotypes of the Hepatitis B virus have distinct geographical distributions and are known to influence a number of clinical features of disease and response to treatment. Certain well recognised viral mutations are also known to influence clinical risk of cirrhosis and hepatocellular carcinoma but in addition may have implications for vaccination programs and screening of blood for donation. This review examines the current state of knowledge about genotype and viral variants of CHB and their utility in the management of this disease.
Publish Date	2015-03-31 15:58
Citation	Croagh CMN, Desmond PV, Bell SJ. Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance. World J Hepatol 2015; 7(3): 289-303
URL	http://www.wjgnet.com/1948-5182/full/v7/i3/289.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i3.289

Full Article (PDF)	WJH-7-289.pdf
Full Article (Word)	WJH-7-289.doc
Manuscript File	14034-Review.docx
Answering Reviewers	14034-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14034-Conflict-of-interest statement.pdf
Copyright License Agreement	14034-Copyright assignment.pdf
Peer-review Report	14034-Peer review(s).pdf
Scientific Misconduct Check	14034-CrossCheck.jpg
Scientific Editor Work List	14034-Scientific editor work list.pdf