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Publication Name World Journal of Gastroenterology
Manuscript ID 1405
Country/Territory China
Received
2012-12-07 16:09
Peer-Review Started
2012-12-10 11:57
To Make the First Decision
2012-12-28 17:33
Return for Revision
2012-12-28 20:50
Revised
2013-01-17 16:02
Second Decision
2013-02-28 18:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-03-01 06:23
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-04-25 18:41
Typeset the Manuscript
2013-05-17 20:38
Publish the Manuscript Online
2013-05-28 09:36
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biotechnology & Applied Microbiology
Manuscript Type Autobiography
Article Title Protective effects of two Lactobacillus plantarum strains in hyperlipidemic mice
Manuscript Source Invited Manuscript
All Author List Li-Xin Wang, Kai Liu, Da-Wei Gao and Ji-Kui Hao
Funding Agency and Grant Number
Funding Agency Grant Number
Chinese Ministry of Education Doctor Degree grant 20101333120011
Hebei Province Natural Science Fund C2011203137
Hebei Province Natural Science Fund 11965152D
Chinese Postdoctoral grant 480013
Corresponding Author Dr. Da-Wei Gao, Department of Biological Engineering, College of Environmental and Chemical Engineering, Yanshan University, No. 438 Hebei Street, Qinhuangdao 066004, Hebei Province, China. dwgao@ysu.edu.cn
Key Words Lactobacillus plantarum; Hypolipidemic; Nuclear factor erythroid 2-related factor 2; Metabolic syndrome; Hepatic steatosis; Cardiovascular disease
Core Tip Protective effects of Lactobacillus plantarum (L. plantarum) CAI6 and L. plantarum SC4 strains on hyperlipidemic mice were found, including regulating lipid metabolism, alleviating hepatic steatosis and reducing cardiovascular disease (CVD) risk. The mechanism of intracorporal antioxidation of Lactobacillus strains may be related to stimulation of nuclear factor-erythroid 2-related factor 2 (Nrf2) expression. Hypolipidemic effect and Nrf2-induced antioxidative defense may contribute to the reduction of CVD risk. We suggest that food fermented by the strains be used as part of the diet to relieve lipid metabolism related metabolic syndrome and to reduce the risk of CVD.
Publish Date 2013-05-28 09:36
Citation Wang LX, Liu K, Gao DW, Hao JK. Protective effects of two Lactobacillus plantarum strains in hyperlipidemic mice. World J Gastroenterol 2013; 19(20): 3150-3156
URL http://www.wjgnet.com/1007-9327/full/v19/i20/3150.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i20.3150
Full Article (PDF) WJG-19-3150.pdf
Manuscript File 1405-Review.doc
Answering Reviewers 1405-Answering reviewers.doc
Copyright License Agreement 1405-Copyright assignment.pdf
Peer-review Report 1405-Peer review(s).docx
Scientific Editor Work List 1405-Scientific editor work list.doc