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3/9/2015 3:58:00 PM | Browse: 1113 | Download: 1363
Publication Name World Journal of Gastroenterology
Manuscript ID 14127
Country China
Received
2014-09-21 08:52
Peer-Review Started
2014-09-21 09:09
To Make the First Decision
2014-10-14 17:04
Return for Revision
2014-10-19 13:12
Revised
2014-11-06 21:48
Second Decision
2014-11-25 18:03
Accepted by Journal Editor-in-Chief
2014-11-25 23:38
Accepted by Company Editor-in-Chief
2014-12-08 16:15
Articles in Press
2014-12-08 17:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-12-19 00:18
Typeset the Manuscript
2015-02-26 12:02
Publish the Manuscript Online
2015-03-09 15:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Angiopoietin and vascular endothelial growth factor expression in colorectal disease models
Manuscript Source Unsolicited Manuscript
All Author List Wei-Xin Liu, Shou-Zhi Gu, Shen Zhang, Yi Ren, Li-Xuan Sang and Cong Dai
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Project of Liaoning Province 2013225303
Science and Technology Project of Shenyang City F13-316-1-40
Corresponding Author Wei-Xin Liu, Professor, Department of Gastroenterology, First Affiliated Hospital, China Medical University, No. 155 North Nanjing Street, Heping District, Shenyang 110001, Liaoning Province, China. weixinliu@yahoo.com
Key Words Angiopoietin-1; Angiopoietin-2; Colorectal cancer; Tie-2; Ulcerative colitis; Vascular endothelial growth factor
Core Tip Colorectal cancer is the most severe complication in ulcerative colitis. Angiopoietin (Ang)-1, Ang-2, their receptor, tyrosine kinase with immunoglobulin-like and EGF-like domains (Tie)-2, and vascular endothelial growth factor may play a key role in forming vasculature which is involved in carcinogenesis. In this study, rats with ulcerative colitis and colorectal cancer had increased expression of these proteins, which suggests they may contribute to the development of colon cancer, chronic colitis, and pathologic angiogenesis in the rat.
Publish Date 2015-03-09 15:58
Citation Liu WX, Gu SZ, Zhang S, Ren Y, Sang LX, Dai C. Angiopoietin and vascular endothelial growth factor expression in colorectal disease models. World J Gastroenterol 2015; 21(9): 2645-2650
URL http://www.wjgnet.com/1007-9327/full/v21/i9/2645.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i9.2645
Full Article (PDF) WJG-21-2645.pdf
Full Article (Word) WJG-21-2645.doc
Manuscript File 14127-Review.doc
Answering Reviewers 14127-Answering reviewers.pdf
Copyright License Agreement 14127-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 14127-Language certificate.pdf
Peer-review Report 14127-Peer reviews.pdf
Scientific Misconduct Check 14127-CrossCheck.jpg
Scientific Editor Work List 14127-Scientific editor work list.doc