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Articles Published Processes
6/18/2015 5:31:00 PM | Browse: 881 | Download: 1038
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Received |
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2014-09-21 08:55 |
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Peer-Review Started |
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2014-09-21 09:02 |
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To Make the First Decision |
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2014-10-14 17:04 |
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Return for Revision |
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2014-10-19 14:56 |
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Revised |
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2014-12-03 20:38 |
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Second Decision |
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2015-01-19 08:26 |
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Accepted by Journal Editor-in-Chief |
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2015-01-19 18:47 |
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Accepted by Company Editor-in-Chief |
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2015-01-21 17:00 |
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Articles in Press |
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2015-01-21 17:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-04-15 11:29 |
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Typeset the Manuscript |
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2015-05-22 15:47 |
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Publish the Manuscript Online |
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2015-06-18 17:32 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Detection of superficial esophageal squamous cell neoplasia by chromoendoscopy-guided confocal laser endomicroscopy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jin Huang, Yun-Sheng Yang, Zhong-Sheng Lu, Shuang-Fang Wang, Jing Yang and Jing Yuan |
| Funding Agency and Grant Number |
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| Corresponding Author |
Yun-Sheng Yang, Professor, Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, No. 28 Fuxing Road, 100853 Beijing, China. huangjin034@163.com |
| Key Words |
Superficial esophageal neoplasia; Squamous cell neoplasm; Confocal endomicroscopy; Endoscopic submucosal dissection; Chromoendoscopy |
| Core Tip |
The aim of the present study was to determine the diagnostic potential of confocal laser endomicroscopy (CLE) combined with Lugol’s iodine chromoendoscopy in detecting superficial esophageal squamous cell neoplasia (ESCN). Lugol’s chromoendoscopy-guided CLE was performed in 52 enrolled patients. In the same patients, chromoendoscopy-guided biopsy was performed by another endoscopist. A comparison of the detection rates between the CLE finding and biopsy was performed. The sensitivity, specificity, negative predictive value and positive predictive value of chromoendoscopy-guided CLE were 95.7%, 90%, 81.8% and 97.8%, respectively. There was a statistically significant difference in the detection of dysplasia between chromoendoscopy-guided CLE and biopsy. Lugol’s chromoendoscopy-guided CLE is a real-time, non-invasive endoscopic diagnostic technology; the accuracy of the detection of superficial ESCN is equivalent to or may be superior to biopsy histology. |
| Publish Date |
2015-06-18 17:32 |
| Citation |
Huang J, Yang YS, Lu ZS, Wang SF, Yang J, Yuan J. Detection of superficial esophageal squamous cell neoplasia by chromoendoscopy-guided confocal laser endomicroscopy. World J Gastroenterol 2015; 21(22): 6974-6981 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i22/6974.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i22.6974 |
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