Publication Name	World Journal of Diabetes
Manuscript ID	14173
Country	United States

Received	2014-09-23 08:23
Peer-Review Started	2014-09-23 18:36
To Make the First Decision	2014-10-28 14:19
Return for Revision	2014-11-03 14:03
Revised	2014-11-06 10:59
Second Decision	2014-11-21 12:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-10 17:36
Articles in Press	2014-12-10 17:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-15 16:59
Publish the Manuscript Online	2015-01-31 14:38

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Topic Highlights
Article Title	Insulin sensitivity and complications in type 1 diabetes: New insights
Manuscript Source	Invited Manuscript
All Author List	Petter Bjornstad, Janet K Snell-Bergeon, Kristen J Nadeau and David M Maahs
Funding Agency and Grant Number
Corresponding Author	Petter Bjornstad, MD, Barbara Davis Center for Diabetes, University of Colorado School of Medicine, 13123 East 16th Avenue, Aurora, CO 80045, United States. petter.bjornstad@childrenscolorado.org
Key Words	Type 1 diabetes; Insulin sensitivity; Vascular complications; Hyperfiltration; Cystatin C; Creatinine; Glomerular filtration rate
Core Tip	Adolescents and adults with type 1 diabetes have reduced insulin sensitivity compared to their non-diabetic counterparts. Reduced insulin sensitivity is implicated in the development and progression of micro and macrovascular complications in type 1 diabetes. Clinical trials are underway investigating insulin sensitivity as a therapeutic target to prevent vascular complications in type 1 diabetes. Methods are needed to identify which patients with type 1 diabetes would benefit from treatment of insulin resistance and translation of this to clinical practice.
Publish Date	2015-01-31 14:38
Citation	Bjornstad P, Snell-Bergeon JK, Nadeau KJ, Maahs DM. Insulin sensitivity and complications in type 1 diabetes: New insights. World J Diabetes 2015; 6(1): 8-16
URL	http://www.wjgnet.com/1948-9358/full/v6/i1/8.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i1.8

Manuscript File	14173-Review.docx
Answering Reviewers	14173-Answering reviewers.pdf
Copyright License Agreement	14173-Copyright assignment.pdf
Peer-review Report	14173-Peer review(s).pdf
Scientific Misconduct Check	14173-CrossCheck.jpg
Scientific Editor Work List	14173-Scientific editor work list.pdf