Publication Name	World Journal of Orthopedics
Manuscript ID	14349
Country	United Kingdom

Received	2014-09-29 08:16
Peer-Review Started	2014-09-29 10:45
To Make the First Decision	2014-10-14 17:25
Return for Revision	2014-10-20 08:07
Revised
Second Decision	2015-01-09 19:30
Accepted by Journal Editor-in-Chief	2015-01-10 15:52
Accepted by Executive Editor-in-Chief	2015-01-19 13:28
Articles in Press	2015-01-19 13:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-25 14:16
Publish the Manuscript Online	2015-04-08 15:18

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Review
Article Title	Knee salvage procedures: The indications, techniques and outcomes of large osteochondral allografts
Manuscript Source	Invited Manuscript
All Author List	Karen Chui, Lee Jeys and Martyn Snow
Funding Agency and Grant Number
Corresponding Author	Dr. Martyn Snow, the Royal Orthopaedic Hospital, Northfield, Birmingham B31 2AP, United Kingdom. snowmartyn@gmail.com
Key Words	Osteochondral allograft; Knee; Salvage; Shell; Dowel
Core Tip	Osteochondral allograft transplantation has been demonstrated to be a safe and effective treatment of large osteochondral and chondral defects of the knee in appropriately selected patients. The treatment reduces pain, improves function and is a viable limb salvage procedure for patients, especially young and active patients for whom total knee arthroplasty is not recommended. Current recommendations for fresh allografts stored at 4C advise implantation within 21-28 d of procurement for optimum chondrocyte viability, following screening and testing protocols. Higher rates of successful allograft transplantation are observed in younger patients, unipolar lesions, normal or corrected malalignment, and defects that are treated within 12 mo of symptom onset.
Publish Date	2015-04-08 15:18
Citation	Chui K, Jeys L, Snow M. Knee salvage procedures: The indications, techniques and outcomes of large osteochondral allografts. World J Orthop 2015; 6(3): 340-350
URL	http://www.wjgnet.com/2218-5836/full/v6/i3/340.htm
DOI	http://dx.doi.org/10.5312/wjo.v6.i3.340

Full Article (PDF)	WJO-6-340.pdf
Full Article (Word)	WJO-6-340.doc
Manuscript File	14349-Peer-review(s).pdf
Answering Reviewers	14349-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14349-Conflict of interest statement.pdf
Copyright License Agreement	14349-Copyright assignment.pdf
Peer-review Report	14349-Peer-review(s).pdf
Scientific Misconduct Check	14349-CorssCheck.jpg
Scientific Editor Work List	14349-Scientific editor work list.pdf