Publication Name	World Journal of Gastroenterology
Manuscript ID	14371
Country	Netherlands

Received	2014-09-30 09:33
Peer-Review Started	2014-09-30 17:20
To Make the First Decision	2014-10-14 16:49
Return for Revision	2014-10-20 10:06
Revised	2014-11-19 00:00
Second Decision	2015-02-10 21:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-02-11 14:57
Articles in Press	2015-02-11 16:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-22 15:20
Publish the Manuscript Online	2015-05-13 10:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Fecal microbiota transplantation as novel therapy in gastroenterology: A systematic review
Manuscript Source	Unsolicited Manuscript
All Author List	Noortje G Rossen, John K MacDonald, Elisabeth M de Vries, Geert R D'Haens, Willem M de Vos, Erwin G Zoetendal and Cyriel Y Ponsioen
Funding Agency and Grant Number	Funding Agency Grant Number Dutch Digestive Foundation” Grant 2011 WO 11-17(to Rossen NG)
Corresponding Author	Noortje G Rossen, MD, Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, Room C2-231, 1105 AZ Amsterdam, The Netherlands. n.g.rossen@amc.uva.nl
Key Words	Fecal microbiota transplantation; Microbiota; Clostridium difficile infection; Inflammatory bowel disease; Metabolic syndrome
Core Tip	Aberrancies in the host’s microbiota have been found in several diseases. The most radical way to modulate the microbiota is by fecal microbiota transplantation (FMT). FMT is already used for various diseases while evidence from randomized studies is only just emerging. We systematically reviewed the efficacy of FMT in Clostridium difficile infection (CDI), inflammatory bowel disease, constipation, irritable bowel syndrome, pouchitis, and metabolic syndrome. FMT could be incorporated in clinical practice for CDI; patients with other indications should currently only be treated in clinical trials. Upcoming randomized studies on the long-term efficacy and safety of FMT will be helpful in the implication of FMT in clinical practice.
Publish Date	2015-05-13 10:38
Citation	Rossen NG, MacDonald JK, de Vries EM, D’Haens GR, de Vos WM, Zoetendal EG, Ponsioen CY. Fecal microbiota transplantation as novel therapy in gastroenterology: A systematic review. World J Gastroenterol 2015; 21(17): 5359-5371
URL	http://www.wjgnet.com/1007-9327/full/v21/i17/5359.htm
DOI	http://www.wjgnet.com/1007-9327/full/v21/i17/5359.htm

Manuscript File	14371-Review.doc
Answering Reviewers	14371-Answering reviewers.pdf
Biostatistics Review Certificate	14371-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	14371-Conflict-of-interest statement.pdf
Copyright License Agreement	14371-Copyright assignment.pdf
Peer-review Report	14371-Peer-review(s).pdf
Scientific Misconduct Check	14371-Scientific misconduct check.pdf
Scientific Editor Work List	14371-Scientific editor work list.pdf