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Articles Published Processes
6/30/2015 8:56:00 AM | Browse: 1000 | Download: 1627
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Received |
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2014-09-30 11:50 |
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Peer-Review Started |
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2014-10-01 09:34 |
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To Make the First Decision |
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2014-10-28 14:34 |
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Return for Revision |
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2014-10-30 19:26 |
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Revised |
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2014-12-08 08:50 |
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Second Decision |
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2015-03-11 13:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2015-03-20 10:29 |
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Articles in Press |
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2015-03-20 10:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-06-10 18:48 |
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Publish the Manuscript Online |
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2015-06-30 08:56 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
Utility of tricalcium phosphate and osteogenic matrix cell sheet constructs for bone defect reconstruction
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tomoyuki Ueha, Manabu Akahane, Takamasa Shimizu, Yoshinobu Uchihara, Yusuke Morita, Naoya Nitta, Akira Kido, Yusuke Inagaki, Kenji Kawate and Yasuhito Tanaka |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Young Scientists (KAKENHI) |
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| Corresponding Author |
Manabu Akahane, MD, PhD, Department of Public Health, Health Management and Policy, Nara Medical University Faculty of Medicine, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan. makahane@naramed-u.ac.jp |
| Key Words |
Bone marrow stromal cells; Osteogenesis; Bone regeneration; Tissue engineering; Calcium phosphate |
| Core Tip |
The treatment of bone defects is a common clinical problem for orthopedic surgeons. Artificial bone combined with cultured bone marrow stromal cells (BMSCs) has been examined and applied for the treatment of clinical cases such as small bone defects. In the present study, we developed constructs of BMSCs and beta-tricalcium phosphate (TCP) combined with osteogenic matrix cell sheets (BMSC/TCP/Sheet constructs), which showed a vigorous osteogenic potential compared with conventionally engineered bone tissue structures consisting of BMSC/TCP constructs. The BMSC/TCP/Sheet constructs will be useful for reconstruction of hard tissues, such as bone defects, as new tissue-engineered bone. |
| Publish Date |
2015-06-30 08:56 |
| Citation |
Ueha T, Akahane M, Shimizu T, Uchihara Y, Morita Y, Nitta N, Kido A, Inagaki Y, Kawate K, Tanaka Y. Utility of tricalcium phosphate and osteogenic matrix cell sheet constructs for bone defect reconstruction. World J Stem Cells 2015; 7(5): 873-882 |
| URL |
http://www.wjgnet.com/1948-0210/full/v7/i5/873.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v7.i5.873 |
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