Publication Name	World Journal of Gastroenterology
Manuscript ID	14466
Country	Türkiye

Received	2014-10-06 13:10
Peer-Review Started	2014-10-06 20:20
To Make the First Decision	2014-11-14 18:50
Return for Revision	2014-11-18 19:19
Revised	2014-11-28 01:35
Second Decision	2014-12-12 17:06
Accepted by Journal Editor-in-Chief	2014-12-14 13:35
Accepted by Executive Editor-in-Chief	2014-12-22 16:53
Articles in Press	2014-12-22 17:22
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-01-06 08:51
Typeset the Manuscript	2015-01-30 15:29
Publish the Manuscript Online	2015-02-11 17:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pathology
Manuscript Type	Basic Study
Article Title	Digitally reinforced hematoxylin-eosin polarization technique in diagnosis of rectal amyloidosis
Manuscript Source	Unsolicited Manuscript
All Author List	Basak Doganavsargil, Gulruh Emiroglu Buberal, Huseyin Toz, Banu Sarsik, Burcin Pehlivanoglu, Murat Sezak and Sait Sen
Funding Agency and Grant Number
Corresponding Author	Basak Doganavsargil, MD, Department of Pathology, Ege University Faculty of Medicine, Bornova, Izmir 35100, Turkey. bdoganavsargil@yahoo.com
Key Words	Amyloidosis; Congo red; Hematoxylin-eosin; Microscopy; Polarization; Rectum
Core Tip	Amyloid fibrils show a faint birefringence with polarization microscopy even when they are stained with hematoxylin-eosin (HE), and this effect can be rein?forced when digital images are captured. We researched the efficacy of this technique in rectal biopsies and observed that it allowed identification of unsuspected cases with HE. True positivity was higher, and false negativity and positivity were lower compared to evalu?ation by HE. Therefore it can be used as an adjunct or a prior step to Congo-red staining, especially for cases with limited tissues for further analysis as it is a fast and safe method.
Publish Date	2015-02-11 17:56
Citation	Doganavsargil B, Buberal GE, Toz H, Sarsik B, Pehlivanoglu B, Sezak M, Sen S. Digitally reinforced hematoxylin-eosin polarization technique in diagnosis of rectal amyloidosis. World J Gastroenterol 2015; 21(6): 1827-1837
URL	http://www.wjgnet.com/1007-9327/full/v21/i6/1827.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i6.1827

Full Article (PDF)	WJG-21-1827.pdf
Full Article (Word)	WJG-21-1827.doc
Manuscript File	14466-Review.doc
Answering Reviewers	14466-Answering reviewers.pdf
Biostatistics Review Certificate	14466-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	14466-Conflict-of-interest statement.pdf
Copyright License Agreement	14466-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	14466-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	14466-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	14466-Language certificate.pdf
Peer-review Report	14466-Peer review(s).pdf
Scientific Misconduct Check	14466-CrossCheck.jpg
Scientific Editor Work List	14466-Scientific editor work list.pdf