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Articles Published Processes
2/12/2015 10:27:00 AM | Browse: 1111 | Download: 1450
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Received |
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2014-10-08 08:46 |
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Peer-Review Started |
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2014-10-08 17:59 |
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To Make the First Decision |
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2014-10-28 14:24 |
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Return for Revision |
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2014-11-01 19:26 |
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Revised |
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2014-11-12 18:37 |
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Second Decision |
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2014-11-28 14:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-12-10 17:22 |
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Articles in Press |
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2014-12-10 17:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-28 19:06 |
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Publish the Manuscript Online |
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2015-02-12 10:27 |
ISSN |
2220-3168 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Minireviews |
Article Title |
Contribution of miRNAs to ion-channel remodelling in atrial fibrillation
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Manuscript Source |
Invited Manuscript |
All Author List |
José Manuel Vilches, Diego Franco and Amelia E Aránega |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Ministerio de Economíay Competitividad, Gobierno de España |
BFU2012-38111 |
Junta de Andalucia |
CTS-1614 |
Junta de Andalucia |
P08-CTS-03878 |
Junta de Andalucia |
BIO-302 |
AFM |
AFM2012-16074 |
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Corresponding Author |
Amelia E Aránega, PhD, Cardiac and Skeletal Myogenesis Group, Department of Experimental Biology, University of Jaén, CU Las Lagunillas B3-362, 23071 Jáen,
Spain. aaranega@ujaen.es
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Key Words |
Atrial fibrillation; MicroRNA; Ion channels; Electrical remodelling |
Core Tip |
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice associated with pronounced mortality and morbidity. MicroRNAs (miRNAs), which are approximately 22 nucleotide long RNA regulators of gene expression, have become a major focus of research in molecular biology miRNAs have emerged as key post-transcriptional regulators of gene expression therefore, it is important to comment on the roles of these small non-protein-coding mRNAs in the cardiovascular system and their involvement in AF. In this review, we summarize the mechanism of miRNAs as regulators of ion-channels genes and their role in electrical remodelling caused by AF.
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Publish Date |
2015-02-12 10:27 |
Citation |
Vilches JM, Franco D, Aránega AE. Contribution of miRNAs to ion-channel remodelling in atrial fibrillation. World J Hypertens 2015; 5(1): 6-13 |
URL |
http://www.wjgnet.com/2220-3168/full/v5/i1/6.htm |
DOI |
http://dx.doi.org/10.5494/wjh.v5.i1.6 |
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