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3/9/2015 3:58:00 PM | Browse: 442 | Download: 508
Publication Name World Journal of Gastroenterology
Manuscript ID 14557
Country of Manuscript Source Japan
Received
2014-10-13 08:58
Peer-Review Started
2014-10-13 21:02
To Make the First Decision
2014-10-29 15:01
Return for Revision
2014-11-03 10:25
Revised
2014-11-13 17:29
Second Decision
2014-12-16 15:27
Accepted by Journal Editor-in-Chief
2014-12-17 17:43
Accepted by Company Editor-in-Chief
2014-12-22 17:02
Articles in Press
2014-12-22 17:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-02-27 13:46
Publish the Manuscript Online
2015-03-09 15:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Pathology
Manuscript Type Retrospective Study
Article Title Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine
Manuscript Source Unsolicited Manuscript
All Author List Reiko Kumagai, Kenichi Kohashi, Shunsuke Takahashi, Hidetaka Yamamoto, Minako Hirahashi, Kenichi Taguchi, Kenichi Nishiyama and Yoshinao Oda
Funding Agency and Grant Number
Corresponding author Dr. Yoshinao Oda, Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. oda@surgpath.med.kyushu-u.ac.jp
Keywords Small intestine; Adenocarcinoma; Mucin; CD10; Microsatellite instability
Core Tip This study analyzed the immunohistochemical expression of mucin core proteins (MUC5AC, MUC6 and MUC2), CD10 and mismatch-repair proteins (MLH1, MSH2), microsatellite instability (MSI), and the mutational status of KRAS and BRAF in 47 primary small intestinal adenocarcinoma. We suggest that the mucin phenotype and CD10 expression of small intestinal adenocarcinoma correlates with biological behavior, genetic alteration, and MSI status. Notably, the preservation of CD10 expression may be correlated with favorable biological behavior. The SIA with co-expression of MUC5AC and MUC2 was correlated with MSI-H status and mucinous adenocarcinoma, similar to colorectal carcinoma.
Publish Date 2015-03-09 15:58
Citation Kumagai R, Kohashi K, Takahashi S, Yamamoto H, Hirahashi M, Taguchi K, Nishiyama K, Oda Y. Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine. World J Gastroenterol 2015; 21(9): 2700-2710
Url http://www.wjgnet.com/1007-9327/full/v21/i9/2700.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i9.2700
Full Article (PDF) WJG-21-2700.pdf
Full Article (Word) WJG-21-2700.doc
Manuscript File 14557-Review.docx
Answering Reviewers 14557-Answering reviewers.pdf
Biostatistics Review Certificate 14557-Biostatistics statement.pdf
Clinical Trial Registration Statement 14557-Institutional Review Board statement.pdf
Conflict-of-Interest Disclosure Form 14557-Conflict-of-interest statement.pdf
Copyright License Agreement 14557-Copyright assignment.pdf
Data Sharing Statement 14557-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) 14557-Institutional Review Board statement.pdf
Institutional Review Board Approval Form or Document 14557-Institutional Review Board statement.pdf
Non-Native Speakers of English Editing Certificate Editing_Certificate_20141011204632.pdf
Peer-review Report 14557-Peer review(s).pdf
Scientific Misconduct Check 14557-CorssCheck.jpg
Scientific Editor Work List 14557-Scientific editor work list.pdf