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Articles Published Processes
3/9/2015 3:58:00 PM | Browse: 1225 | Download: 2251
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Received |
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2014-10-13 08:58 |
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Peer-Review Started |
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2014-10-13 21:02 |
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To Make the First Decision |
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2014-10-29 15:01 |
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Return for Revision |
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2014-11-03 10:25 |
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Revised |
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2014-11-13 17:29 |
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Second Decision |
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2014-12-16 15:27 |
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Accepted by Journal Editor-in-Chief |
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2014-12-17 17:43 |
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Accepted by Executive Editor-in-Chief |
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2014-12-22 17:02 |
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Articles in Press |
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2014-12-22 17:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-02-27 13:46 |
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Publish the Manuscript Online |
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2015-03-09 15:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Reiko Kumagai, Kenichi Kohashi, Shunsuke Takahashi, Hidetaka Yamamoto, Minako Hirahashi, Kenichi Taguchi, Kenichi Nishiyama and Yoshinao Oda |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Yoshinao Oda, Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. oda@surgpath.med.kyushu-u.ac.jp |
| Key Words |
Small intestine; Adenocarcinoma; Mucin; CD10; Microsatellite instability |
| Core Tip |
This study analyzed the immunohistochemical expression of mucin core proteins (MUC5AC, MUC6 and MUC2), CD10 and mismatch-repair proteins (MLH1, MSH2), microsatellite instability (MSI), and the mutational status of KRAS and BRAF in 47 primary small intestinal adenocarcinoma. We suggest that the mucin phenotype and CD10 expression of small intestinal adenocarcinoma correlates with biological behavior, genetic alteration, and MSI status. Notably, the preservation of CD10 expression may be correlated with favorable biological behavior. The SIA with co-expression of MUC5AC and MUC2 was correlated with MSI-H status and mucinous adenocarcinoma, similar to colorectal carcinoma. |
| Publish Date |
2015-03-09 15:58 |
| Citation |
Kumagai R, Kohashi K, Takahashi S, Yamamoto H, Hirahashi M, Taguchi K, Nishiyama K, Oda Y. Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine. World J Gastroenterol 2015; 21(9): 2700-2710 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i9/2700.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i9.2700 |
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