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Articles Published Processes
12/2/2015 11:56:00 AM | Browse: 938 | Download: 1706
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Received |
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2014-10-13 08:49 |
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Peer-Review Started |
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2014-10-13 15:34 |
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To Make the First Decision |
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2014-12-26 13:19 |
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Return for Revision |
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2015-01-01 14:06 |
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Revised |
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2015-01-09 00:57 |
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Second Decision |
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2015-04-01 14:52 |
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Accepted by Journal Editor-in-Chief |
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2015-04-01 18:11 |
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Accepted by Executive Editor-in-Chief |
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2015-04-09 16:42 |
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Articles in Press |
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2015-04-09 16:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-05-29 18:02 |
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Publish the Manuscript Online |
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2015-06-19 15:32 |
| ISSN |
2220-3192 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Protective effect of fu-qi granule on carbon tetrachloride-induced liver fibrosis in rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin Zhong, Yan-Ling Sun, Wen-Li Shi, Xiao Ma, Zhe Chen, Jia-Bo Wang, Rui-Sheng Li, Xue-Ai Song, Hong-Hong Liu, Yan-Ling Zhao and Xiao-He Xiao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Sciences Foundation |
81173571 |
| National Basic Research Program of China |
2007CB512607 |
| Major Projects of the National Science and Technology |
2012ZX10005010-002-002 |
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| Corresponding Author |
Yan-Ling Zhao, Professor, China Military Institute of Chinese Medicine, 302 Military Hospital of China, 100#, the 4th Ring Road, Beijing 100039,
China. zhaoyl2855@126.com
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| Key Words |
Protective effect; Fu-qi granule; Carbon tetrachloride; Mammalian target of rapamycin/p70S6K signal pathway; Liver fibrosis |
| Core Tip |
Fu-qi granule (FQG) is traditional Chinese medicine preparation to prove the antifibrotic properties of traditional Chinese drug composed of six medicinal herbs in rats treated with carbon tetrachloride. we checked activities of liver enzymes, histopathological changes within the liver as well as the expression of mammalian target of rapamycin (mTOR) and hypoxia-inducible factor-1 and tissue inhibitor of matrix metalloproteinases-1 and matrix metalloproteinases-9. FQG can attenuate liver fibrosis induced by carbon tetrachloride via mTOR/p70S6K signal transduction pathway.
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| Publish Date |
2015-06-19 15:32 |
| Citation |
Zhong L, Sun YL, Shi WL, Ma X, Chen Z, Wang JB, Li RS, Song XA, Liu HH, Zhao YL, Xiao XH. Protective effect of fu-qi granule on carbon tetrachloride-induced liver fibrosis in rats. World J Pharmacol 2015; 4(2): 227-235 |
| URL |
http://www.wjgnet.com/2220-3192/full/v4/i2/227.htm |
| DOI |
http://dx.doi.org/10.5497/wjp.v4.i2.227 |
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