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Articles Published Processes
12/10/2015 10:35:00 AM | Browse: 1266 | Download: 1774
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Received |
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2014-10-14 08:20 |
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Peer-Review Started |
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2014-10-14 19:54 |
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To Make the First Decision |
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2014-12-11 20:28 |
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Return for Revision |
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2014-12-16 15:40 |
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Revised |
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2014-12-18 00:23 |
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Second Decision |
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2015-01-30 11:15 |
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Accepted by Journal Editor-in-Chief |
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2015-02-01 21:46 |
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Accepted by Executive Editor-in-Chief |
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2015-02-05 17:16 |
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Articles in Press |
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2015-02-05 17:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-03-08 19:16 |
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Publish the Manuscript Online |
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2015-03-19 16:57 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Minireviews |
Article Title |
Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy
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Manuscript Source |
Invited Manuscript |
All Author List |
Massimo Donadelli, Ilaria Dando, Elisa Dalla Pozza and Marta Palmieri |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Associazione Italiana Ricerca Cancro, Milan, Italy |
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Fondazione CariPaRo, Padova, Italy |
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Ministero dell’Istruzione, dell’Università e della Ricerca, Rome, Italy |
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Corresponding Author |
Massimo Donadelli, PhD, Professor, Department of Life and Reproduction Sciences, Biochemistry Section, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy. massimo.donadelli@univr.it |
Key Words |
Uncoupling protein 2; Target therapy; Reactive oxygen species; Metabolism; Pancreatic cancer |
Core Tip |
The dramatic poor prognosis of pancreatic cancer forces towards the identification of novel efficient therapeutic targets against this neoplasia. Overexpression of uncoupling protein 2 (UCP2) and its functional involvement in cancer development, reactive oxygen species production, and cancer metabolic reprogramming may represent the rationale and the starting point for future drug design projects focused on the identification of specific UCP2 inhibitors as innovative therapeutic tool against pancreatic cancer. |
Publish Date |
2015-03-19 16:57 |
Citation |
Donadelli M, Dando I, Dalla Pozza E, Palmieri M. Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy. World J Gastroenterol 2015; 21(11): 3232-3238 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i11/3232.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i11.3232 |
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