Publication Name	World Journal of Gastroenterology
Manuscript ID	14599
Country	China

Received	2014-10-15 08:52
Peer-Review Started	2014-10-16 08:16
To Make the First Decision	2014-11-14 19:06
Return for Revision	2014-11-18 12:11
Revised	2014-11-25 15:09
Second Decision	2015-01-19 08:28
Accepted by Journal Editor-in-Chief	2015-01-19 19:33
Accepted by Executive Editor-in-Chief	2015-01-21 17:01
Articles in Press	2015-01-21 17:29
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-02-04 20:15
Typeset the Manuscript	2015-04-01 20:27
Publish the Manuscript Online	2015-04-20 15:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Controlled Trial
Article Title	Antimicrobial prophylaxis in patients for colorectal lesions undergoing endoscopic resection
Manuscript Source	Unsolicited Manuscript
All Author List	Qi-Sheng Zhang, Bing Han, Jian-Hua Xu, Peng Gao and Yu-Cui Shen
Funding Agency and Grant Number
Corresponding Author	Qi-Sheng Zhang, MD, Digestive Endoscopy Center, Department of Gastroenterology and Hepatology, Branch of Shanghai First People’s Hospital, Jiaotong University, No. 1878 North Sichuan Road, Hongkou District, Shanghai 200081, China. zhangqish@hotmail.com
Key Words	Antibiotic prophylaxis; Endoscopic mucosal resection; Endoscopic submucosal dissection; Adverse events; Cefuroxime
Core Tip	We designed a control, randomized study to investigate effect of prophylaxis antibiotics on clinic adverse events in patients underwent endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR) procedure for colorectal lesions, and observe the value of surgical wound area as a risk factor. The clinical adverse events (abdominal pain, diarrhea, hematochezia and fever), leucocytosis and elevated level of C-reactive protein are not uncommon after EMR or ESD procedures. Prophylaxis antibiotics can reduce the incidence of clinical adverse events signicantlly. In addition, when the surgical wound area is larger than 10 mm ? 10 mm, more clinical adverse events would happen.
Publish Date	2015-04-20 15:10
Citation	Zhang QS, Han B, Xu JH, Gao P, Shen YC. Antimicrobial prophylaxis in patients with colorectal lesions undergoing endoscopic resection. World J Gastroenterol 2015; 21(15): 4715-4721
URL	http://www.wjgnet.com/1007-9327/full/v21/i15/4715.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i15.4715

Full Article (PDF)	WJG-21-4715.pdf
Full Article (Word)	WJG-21-4715.doc
Manuscript File	14599-Review.doc
Answering Reviewers	14599-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14599-Conflict-of-interest statement.pdf
Copyright License Agreement	14599-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	14599-Institutional review board statement.pdf
Peer-review Report	14599-Peer-review(s).pdf
Scientific Misconduct Check	14599-CrossCheck.jpg
Scientific Editor Work List	14599-Scientific editor work list.pdf